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Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform.

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Title: Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform.
Authors: Strub MD; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, Iowa, USA., Ramachandran S; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA., Boudko DY; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA., Meleshkevitch EA; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA., Pezzulo AA; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA., Subramanian A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Liberzon A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Bridges RJ; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA., McCray PB Jr; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, Iowa, USA.
Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Feb; Vol. 11 (2), pp. 240-251. Date of Electronic Publication: 2021 Dec 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Strub+MD%22">Strub MD</searchLink>; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Ramachandran+S%22">Ramachandran S</searchLink>; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Boudko+DY%22">Boudko DY</searchLink>; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Meleshkevitch+EA%22">Meleshkevitch EA</searchLink>; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Pezzulo+AA%22">Pezzulo AA</searchLink>; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Subramanian+A%22">Subramanian A</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Liberzon+A%22">Liberzon A</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Bridges+RJ%22">Bridges RJ</searchLink>; Department of Physiology and Biophysics, Rosalind Franklin University, North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22McCray+PB+Jr%22">McCray PB Jr</searchLink>; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.; Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, Iowa, USA.
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      – TitleFull: Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform.
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              Text: 2022 Feb
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