Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity.
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| Title: | Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. |
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| Authors: | Zanou N; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland. nad.zanou.mdphd@gmail.com., Dridi H; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Reiken S; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Imamura de Lima T; Laboratory of Integrative Systems Physiology (LISP), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Donnelly C; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., De Marchi U; Nestlé Research - École Polytechnique Fédérale de Lausanne (EPFL), Innovation Park, Lausanne, Switzerland., Ferrini M; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Vidal J; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Sittenfeld L; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Feige JN; Nestlé Research - École Polytechnique Fédérale de Lausanne (EPFL), Innovation Park, Lausanne, Switzerland.; School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Garcia-Roves PM; Department of Physiological Sciences, School of Medicine and Health Sciences, University of Barcelona and Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Spain., Lopez-Mejia IC; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland., Marks AR; Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY, USA., Auwerx J; Laboratory of Integrative Systems Physiology (LISP), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Kayser B; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Place N; Institute of Sport Sciences and Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland. nicolas.place@unil.ch. |
| Source: | Nature communications [Nat Commun] 2021 Dec 10; Vol. 12 (1), pp. 7219. Date of Electronic Publication: 2021 Dec 10. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-021-27422-1 |
