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PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.

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Title: PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.
Authors: Uddin S; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK. sorif.2.uddin@gsk.com., Amour A; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Lewis DJ; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Edwards CD; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Williamson MG; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Hall S; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Lione LA; Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, Hertfordshire, AL10 9AB, UK., Hessel EM; Eligo Bioscience, 29 Rue du Faubourg Saint-Jacques, 75014, Paris, France.
Source: BMC immunology [BMC Immunol] 2021 Dec 17; Vol. 22 (1), pp. 78. Date of Electronic Publication: 2021 Dec 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966980 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2172 (Electronic) Linking ISSN: 14712172 NLM ISO Abbreviation: BMC Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Uddin+S%22">Uddin S</searchLink>; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK. sorif.2.uddin@gsk.com.<br /><searchLink fieldCode="AU" term="%22Amour+A%22">Amour A</searchLink>; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Lewis+DJ%22">Lewis DJ</searchLink>; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Edwards+CD%22">Edwards CD</searchLink>; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Williamson+MG%22">Williamson MG</searchLink>; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Hall+S%22">Hall S</searchLink>; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Lione+LA%22">Lione LA</searchLink>; Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, Hertfordshire, AL10 9AB, UK.<br /><searchLink fieldCode="AU" term="%22Hessel+EM%22">Hessel EM</searchLink>; Eligo Bioscience, 29 Rue du Faubourg Saint-Jacques, 75014, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22100966980%22">BMC immunology</searchLink> [BMC Immunol] 2021 Dec 17; Vol. 22 (1), pp. 78. <i>Date of Electronic Publication: </i>2021 Dec 17.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100966980 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2172 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712172%22">14712172 </searchLink><i>NLM ISO Abbreviation: </i>BMC Immunol <i>Subsets: </i>MEDLINE
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              Text: 2021 Dec 17
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