PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.
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| Title: | PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation. |
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| Authors: | Uddin S; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK. sorif.2.uddin@gsk.com., Amour A; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Lewis DJ; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Edwards CD; In Vivo/In Vitro Translation, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Williamson MG; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Hall S; Immunology Research Unit, Respiratory Therapy Area Unit, GSK Medicines Research Centre, GlaxoSmithKline Research and Development Limited, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK., Lione LA; Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, Hertfordshire, AL10 9AB, UK., Hessel EM; Eligo Bioscience, 29 Rue du Faubourg Saint-Jacques, 75014, Paris, France. |
| Source: | BMC immunology [BMC Immunol] 2021 Dec 17; Vol. 22 (1), pp. 78. Date of Electronic Publication: 2021 Dec 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100966980 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2172 (Electronic) Linking ISSN: 14712172 NLM ISO Abbreviation: BMC Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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