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SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.

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Title: SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
Authors: Biering SB; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., de Sousa FTG; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Tjang LV; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Pahmeier F; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Ruan R; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Blanc SF; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Patel TS; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Worthington CM; Chan Zuckerberg Biohub, San Francisco, CA, USA., Glasner DR; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA., Castillo-Rojas B; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Servellita V; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA., Lo NTN; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Wong MP; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Warnes CM; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Sandoval DR; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA., Clausen TM; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA., Santos YA; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA., Ortega V; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA., Aguilar HC; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA., Esko JD; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA., Chui CY; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA., Pak JE; Chan Zuckerberg Biohub, San Francisco, CA, USA., Beatty PR; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Harris E; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.; Lead contact.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2021 Dec 13. Date of Electronic Publication: 2021 Dec 13.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
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  Data: <searchLink fieldCode="AU" term="%22Biering+SB%22">Biering SB</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22de+Sousa+FTG%22">de Sousa FTG</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tjang+LV%22">Tjang LV</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pahmeier+F%22">Pahmeier F</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ruan+R%22">Ruan R</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blanc+SF%22">Blanc SF</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Patel+TS%22">Patel TS</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Worthington+CM%22">Worthington CM</searchLink>; Chan Zuckerberg Biohub, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Glasner+DR%22">Glasner DR</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Castillo-Rojas+B%22">Castillo-Rojas B</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Servellita+V%22">Servellita V</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lo+NTN%22">Lo NTN</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wong+MP%22">Wong MP</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Warnes+CM%22">Warnes CM</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sandoval+DR%22">Sandoval DR</searchLink>; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Clausen+TM%22">Clausen TM</searchLink>; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Santos+YA%22">Santos YA</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ortega+V%22">Ortega V</searchLink>; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.<br /><searchLink fieldCode="AU" term="%22Aguilar+HC%22">Aguilar HC</searchLink>; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.<br /><searchLink fieldCode="AU" term="%22Esko+JD%22">Esko JD</searchLink>; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chui+CY%22">Chui CY</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pak+JE%22">Pak JE</searchLink>; Chan Zuckerberg Biohub, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Beatty+PR%22">Beatty PR</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Harris+E%22">Harris E</searchLink>; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.; Lead contact.
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