Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.

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Title: Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.
Authors: Herder V; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Dee K; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Wojtus JK; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Epifano I; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Goldfarb D; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Rozario C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Gu Q; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Da Silva Filipe A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Nomikou K; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Nichols J; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Jarrett RF; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Stevenson A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., McFarlane S; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Stewart ME; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Szemiel AM; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Pinto RM; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Masdefiol Garriga A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.; University of Glasgow School of Veterinary Medicine, Glasgow, Scotland United Kingdom., Davis C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Allan J; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Graham SV; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Murcia PR; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Boutell C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.
Source: PLoS biology [PLoS Biol] 2021 Dec 21; Vol. 19 (12), pp. e3001065. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3001065