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Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.

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Title: Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.
Authors: Herder V; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Dee K; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Wojtus JK; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Epifano I; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Goldfarb D; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Rozario C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Gu Q; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Da Silva Filipe A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Nomikou K; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Nichols J; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Jarrett RF; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Stevenson A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., McFarlane S; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Stewart ME; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Szemiel AM; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Pinto RM; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Masdefiol Garriga A; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.; University of Glasgow School of Veterinary Medicine, Glasgow, Scotland United Kingdom., Davis C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Allan J; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Graham SV; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Murcia PR; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom., Boutell C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.
Source: PLoS biology [PLoS Biol] 2021 Dec 21; Vol. 19 (12), pp. e3001065. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.
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  Data: <searchLink fieldCode="AU" term="%22Herder+V%22">Herder V</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dee+K%22">Dee K</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wojtus+JK%22">Wojtus JK</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Epifano+I%22">Epifano I</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goldfarb+D%22">Goldfarb D</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rozario+C%22">Rozario C</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gu+Q%22">Gu Q</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Da+Silva+Filipe+A%22">Da Silva Filipe A</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nomikou+K%22">Nomikou K</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nichols+J%22">Nichols J</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jarrett+RF%22">Jarrett RF</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stevenson+A%22">Stevenson A</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22McFarlane+S%22">McFarlane S</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stewart+ME%22">Stewart ME</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Szemiel+AM%22">Szemiel AM</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pinto+RM%22">Pinto RM</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Masdefiol+Garriga+A%22">Masdefiol Garriga A</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.; University of Glasgow School of Veterinary Medicine, Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davis+C%22">Davis C</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Allan+J%22">Allan J</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Graham+SV%22">Graham SV</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Murcia+PR%22">Murcia PR</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boutell+C%22">Boutell C</searchLink>; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, Scotland United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2021 Dec 21; Vol. 19 (12), pp. e3001065. <i>Date of Electronic Publication: </i>2021 Dec 21 (<i>Print Publication: </i>2021).
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