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Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers.

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Title: Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers.
Authors: Nyanhete TE; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Immunology, Duke University School of Medicine, Durham, NC, United States., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States., LaBranche CC; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States., Eaton A; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Dennison SM; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Goodman D; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Janowska K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States., Spreng RL; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States., Zhang L; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Mudrak SV; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Hope TJ; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Hora B; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States., Bradley T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States., Georgiev IS; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, United States., Montefiori DC; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Acharya P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Tomaras GD; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Immunology, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, United States.
Source: Frontiers in immunology [Front Immunol] 2021 Dec 23; Vol. 12, pp. 670561. Date of Electronic Publication: 2021 Dec 23 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers.
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  Data: <searchLink fieldCode="AU" term="%22Nyanhete+TE%22">Nyanhete TE</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Immunology, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Edwards+RJ%22">Edwards RJ</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22LaBranche+CC%22">LaBranche CC</searchLink>; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Mansouri+K%22">Mansouri K</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Eaton+A%22">Eaton A</searchLink>; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Dennison+SM%22">Dennison SM</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Saunders+KO%22">Saunders KO</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Goodman+D%22">Goodman D</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Janowska+K%22">Janowska K</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Spreng+RL%22">Spreng RL</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Mudrak+SV%22">Mudrak SV</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Hope+TJ%22">Hope TJ</searchLink>; Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Hora+B%22">Hora B</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Bradley+T%22">Bradley T</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Medicine, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Georgiev+IS%22">Georgiev IS</searchLink>; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, United States.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Acharya+P%22">Acharya P</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Tomaras+GD%22">Tomaras GD</searchLink>; Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, United States.; Department of Immunology, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, United States.
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