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Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.

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Title: Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.
Authors: Zhang J; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Walker ME; Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sanidad KZ; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Zhang H; State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, SAR, China.; Department of Occupational and Environmental Health, School of Public Health, Qingdao University, Qingdao, China., Liang Y; State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, SAR, China., Zhao E; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Chacon-Vargas K; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Yeliseyev V; Massachusetts Host-Microbiota Center, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Parsonnet J; Department of Medicine and Department of Health Research and Policy, Stanford University, Stanford, CA, USA., Haggerty TD; Department of Medicine and Department of Health Research and Policy, Stanford University, Stanford, CA, USA., Wang G; Department of Food Science, University of Massachusetts, Amherst, MA, USA.; School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China., Simpson JB; Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jariwala PB; Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beaty VV; Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yang J; Department of Entomology and Nematology, University of California, Davis, CA, USA., Yang H; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Panigrahy A; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Minter LM; Department of Veterinary & Animal Sciences, University of Massachusetts, Amherst, MA, USA., Kim D; Department of Mathematics and Statistics, University of Massachusetts, Amherst, MA, USA., Gibbons JG; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Liu L; Eastern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Wyndmoor, PA, USA., Li Z; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Xiao H; Department of Food Science, University of Massachusetts, Amherst, MA, USA., Borlandelli V; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, Netherlands., Overkleeft HS; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, Netherlands., Cloer EW; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Major MB; Department of Cell Biology and Physiology, and Department of Otolaryngology, Washington University, St. Louis, MO, USA., Goldfarb D; Department of Cell Biology and Physiology, Institute for Informatics, Washington University, St. Louis, MO, USA., Cai Z; State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, SAR, China. zwcai@hkbu.edu.hk., Redinbo MR; Departments of Chemistry, Biochemistry, Microbiology and Genomics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. redinbo@unc.edu., Zhang G; Department of Food Science, University of Massachusetts, Amherst, MA, USA. zhanggd@nus.edu.sg.; Department of Food Science and Technology, National University of Singapore, Singapore, Singapore. zhanggd@nus.edu.sg.
Source: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 136. Date of Electronic Publication: 2022 Jan 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Department of Food Science, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chacon-Vargas+K%22">Chacon-Vargas K</searchLink>; Department of Food Science, University of Massachusetts, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yeliseyev+V%22">Yeliseyev V</searchLink>; Massachusetts Host-Microbiota Center, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Parsonnet+J%22">Parsonnet J</searchLink>; Department of Medicine and Department of Health Research and Policy, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Haggerty+TD%22">Haggerty TD</searchLink>; Department of Medicine and Department of Health Research and Policy, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+G%22">Wang G</searchLink>; Department of Food Science, University of Massachusetts, Amherst, MA, USA.; School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Simpson+JB%22">Simpson JB</searchLink>; 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Department of Food Science, University of Massachusetts, Amherst, MA, USA. zhanggd@nus.edu.sg.; Department of Food Science and Technology, National University of Singapore, Singapore, Singapore. zhanggd@nus.edu.sg.
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