The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

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Title: The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.
Authors: Krastev DB; The CRUK Gene Function Laboratory, London, UK.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Li S; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Sun Y; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Wicks AJ; The CRUK Gene Function Laboratory, London, UK.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Hoslett G; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Weekes D; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Badder LM; The Breast Cancer Now Research Unit, King's College London, London, UK., Knight EG; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Marlow R; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Pardo MC; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Yu L; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA., Bartek J; Danish Cancer Society Research Center, Copenhagen, Denmark.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Choudhary JS; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Pommier Y; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Pettitt SJ; The CRUK Gene Function Laboratory, London, UK. Stephen.Pettitt@icr.ac.uk.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Stephen.Pettitt@icr.ac.uk., Tutt ANJ; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Andrew.Tutt@icr.ac.uk., Ramadan K; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK. Kristijan.Ramadan@oncology.ox.ac.uk., Lord CJ; The CRUK Gene Function Laboratory, London, UK. Chris.Lord@icr.ac.uk.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Chris.Lord@icr.ac.uk.
Source: Nature cell biology [Nat Cell Biol] 2022 Jan; Vol. 24 (1), pp. 62-73. Date of Electronic Publication: 2022 Jan 10.
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.
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  Data: <searchLink fieldCode="AU" term="%22Krastev+DB%22">Krastev DB</searchLink>; The CRUK Gene Function Laboratory, London, UK.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wicks+AJ%22">Wicks AJ</searchLink>; The CRUK Gene Function Laboratory, London, UK.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Hoslett+G%22">Hoslett G</searchLink>; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Weekes+D%22">Weekes D</searchLink>; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Badder+LM%22">Badder LM</searchLink>; The Breast Cancer Now Research Unit, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Knight+EG%22">Knight EG</searchLink>; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Marlow+R%22">Marlow R</searchLink>; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Pardo+MC%22">Pardo MC</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Talele+TT%22">Talele TT</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bartek+J%22">Bartek J</searchLink>; Danish Cancer Society Research Center, Copenhagen, Denmark.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Choudhary+JS%22">Choudhary JS</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Pommier+Y%22">Pommier Y</searchLink>; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pettitt+SJ%22">Pettitt SJ</searchLink>; The CRUK Gene Function Laboratory, London, UK. Stephen.Pettitt@icr.ac.uk.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Stephen.Pettitt@icr.ac.uk.<br /><searchLink fieldCode="AU" term="%22Tutt+ANJ%22">Tutt ANJ</searchLink>; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Andrew.Tutt@icr.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ramadan+K%22">Ramadan K</searchLink>; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK. Kristijan.Ramadan@oncology.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lord+CJ%22">Lord CJ</searchLink>; The CRUK Gene Function Laboratory, London, UK. Chris.Lord@icr.ac.uk.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Chris.Lord@icr.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2022 Jan; Vol. 24 (1), pp. 62-73. <i>Date of Electronic Publication: </i>2022 Jan 10.
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