Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder.
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| Title: | Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder. |
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| Authors: | Burton DF; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Boa-Amponsem OM; Integrated Biosciences PhD Program, North Carolina Central University, Durham, North Carolina, USA.; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, USA., Dixon MS; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Hopkins MJ; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Herbin TA; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Toney S; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA., Tarpley M; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA., Rodriguez BV; Department of Biochemistry, Duke University, Durham, North Carolina, USA., Fish EW; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, USA., Parnell SE; Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, North Carolina, USA.; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina, USA., Cole GJ; Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, North Carolina, USA., Williams KP; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, North Carolina, USA.; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina, USA. |
| Source: | Journal of neuroscience research [J Neurosci Res] 2022 Aug; Vol. 100 (8), pp. 1585-1601. Date of Electronic Publication: 2022 Jan 11. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley Interscience Country of Publication: United States NLM ID: 7600111 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4547 (Electronic) Linking ISSN: 03604012 NLM ISO Abbreviation: J Neurosci Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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