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Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability.

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Title: Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability.
Authors: Burke JA; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA., Zhang X; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Bobbala S; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV, USA., Frey MA; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA., Bohorquez Fuentes C; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA., Freire Haddad H; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA., Allen SD; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA., Richardson RAK; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA., Ameer GA; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. g-ameer@northwestern.edu.; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. g-ameer@northwestern.edu.; International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu., Scott EA; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.; International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.
Source: Nature nanotechnology [Nat Nanotechnol] 2022 Mar; Vol. 17 (3), pp. 319-330. Date of Electronic Publication: 2022 Jan 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101283273 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-3395 (Electronic) Linking ISSN: 17483387 NLM ISO Abbreviation: Nat Nanotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability.
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  Data: <searchLink fieldCode="AU" term="%22Burke+JA%22">Burke JA</searchLink>; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bobbala+S%22">Bobbala S</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV, USA.<br /><searchLink fieldCode="AU" term="%22Frey+MA%22">Frey MA</searchLink>; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bohorquez+Fuentes+C%22">Bohorquez Fuentes C</searchLink>; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Freire+Haddad+H%22">Freire Haddad H</searchLink>; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Allen+SD%22">Allen SD</searchLink>; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Richardson+RAK%22">Richardson RAK</searchLink>; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ameer+GA%22">Ameer GA</searchLink>; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. g-ameer@northwestern.edu.; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. g-ameer@northwestern.edu.; International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA. g-ameer@northwestern.edu.<br /><searchLink fieldCode="AU" term="%22Scott+EA%22">Scott EA</searchLink>; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Center for Advanced Regenerative Engineering, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.; Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.; International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA. evan.scott@northwestern.edu.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA. evan.scott@northwestern.edu.
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  Data: <searchLink fieldCode="JN" term="%22101283273%22">Nature nanotechnology</searchLink> [Nat Nanotechnol] 2022 Mar; Vol. 17 (3), pp. 319-330. <i>Date of Electronic Publication: </i>2022 Jan 17.
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              Text: 2022 Mar
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