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Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.

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Title: Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.
Authors: Semmrich M; Department of Research, BioInvent International AB, Lund, Sweden., Marchand JB; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Fend L; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Rehn M; Department of Research, BioInvent International AB, Lund, Sweden., Remy C; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Holmkvist P; Department of Research, BioInvent International AB, Lund, Sweden., Silvestre N; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Svensson C; Department of Research, BioInvent International AB, Lund, Sweden., Kleinpeter P; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Deforges J; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Junghus F; Department of Research, BioInvent International AB, Lund, Sweden., Cleary KL; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Bodén M; Department of Research, BioInvent International AB, Lund, Sweden., Mårtensson L; Department of Research, BioInvent International AB, Lund, Sweden., Foloppe J; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Teige I; Department of Research, BioInvent International AB, Lund, Sweden., Quéméneur E; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Frendéus B; Department of Research, BioInvent International AB, Lund, Sweden bjorn.frendeus@bioinvent.com.; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jan; Vol. 10 (1).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8<superscript>+</superscript> T cell immunity to reject 'cold' tumors.
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  Data: <searchLink fieldCode="AU" term="%22Semmrich+M%22">Semmrich M</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Marchand+JB%22">Marchand JB</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Fend+L%22">Fend L</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Rehn+M%22">Rehn M</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Remy+C%22">Remy C</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Holmkvist+P%22">Holmkvist P</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Silvestre+N%22">Silvestre N</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Svensson+C%22">Svensson C</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Kleinpeter+P%22">Kleinpeter P</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Deforges+J%22">Deforges J</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Junghus+F%22">Junghus F</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Cleary+KL%22">Cleary KL</searchLink>; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Bodén+M%22">Bodén M</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Mårtensson+L%22">Mårtensson L</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Foloppe+J%22">Foloppe J</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Teige+I%22">Teige I</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Quéméneur+E%22">Quéméneur E</searchLink>; Department of Research, Transgene SA, Illkirch-Graffenstaden, France.<br /><searchLink fieldCode="AU" term="%22Frendéus+B%22">Frendéus B</searchLink>; Department of Research, BioInvent International AB, Lund, Sweden bjorn.frendeus@bioinvent.com.; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
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  Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2022 Jan; Vol. 10 (1).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jitc-2021-003488
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        Text: English
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              Text: 2022 Jan
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