Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.
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| Title: | Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors. |
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| Authors: | Semmrich M; Department of Research, BioInvent International AB, Lund, Sweden., Marchand JB; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Fend L; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Rehn M; Department of Research, BioInvent International AB, Lund, Sweden., Remy C; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Holmkvist P; Department of Research, BioInvent International AB, Lund, Sweden., Silvestre N; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Svensson C; Department of Research, BioInvent International AB, Lund, Sweden., Kleinpeter P; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Deforges J; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Junghus F; Department of Research, BioInvent International AB, Lund, Sweden., Cleary KL; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Bodén M; Department of Research, BioInvent International AB, Lund, Sweden., Mårtensson L; Department of Research, BioInvent International AB, Lund, Sweden., Foloppe J; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Teige I; Department of Research, BioInvent International AB, Lund, Sweden., Quéméneur E; Department of Research, Transgene SA, Illkirch-Graffenstaden, France., Frendéus B; Department of Research, BioInvent International AB, Lund, Sweden bjorn.frendeus@bioinvent.com.; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK. |
| Source: | Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jan; Vol. 10 (1). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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