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Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids.

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Title: Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids.
Authors: Cakir B; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Tanaka Y; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec, H1T 2M4, Canada., Kiral FR; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Xiang Y; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Dagliyan O; Department of Neurobiology, Harvard Medical School, Boston, MA, 02115, USA., Wang J; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA., Lee M; Department of Molecular, Cellular, Developmental Biology, Yale University, New Haven, CT, 06520, USA., Greaney AM; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA., Yang WS; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., duBoulay C; Department of Biology, Colby College, Waterville, ME, 06901, USA., Kural MH; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA., Patterson B; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Zhong M; Department of Cell Biology, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Kim J; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA., Bai Y; Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA., Min W; Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA., Niklason LE; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA., Patra P; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Biomedical Engineering, University of Bridgeport, Bridgeport, CT, 06604, USA., Park IH; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA. inhyun.park@yale.edu.
Source: Nature communications [Nat Commun] 2022 Jan 20; Vol. 13 (1), pp. 430. Date of Electronic Publication: 2022 Jan 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids.
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  Data: <searchLink fieldCode="AU" term="%22Cakir+B%22">Cakir B</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec, H1T 2M4, Canada.<br /><searchLink fieldCode="AU" term="%22Kiral+FR%22">Kiral FR</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+Y%22">Xiang Y</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Dagliyan+O%22">Dagliyan O</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Department of Molecular, Cellular, Developmental Biology, Yale University, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Greaney+AM%22">Greaney AM</searchLink>; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Yang+WS%22">Yang WS</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22duBoulay+C%22">duBoulay C</searchLink>; Department of Biology, Colby College, Waterville, ME, 06901, USA.<br /><searchLink fieldCode="AU" term="%22Kural+MH%22">Kural MH</searchLink>; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+B%22">Patterson B</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Zhong+M%22">Zhong M</searchLink>; Department of Cell Biology, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Min+W%22">Min W</searchLink>; Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale School of Medicine, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Niklason+LE%22">Niklason LE</searchLink>; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Patra+P%22">Patra P</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA.; Department of Biomedical Engineering, University of Bridgeport, Bridgeport, CT, 06604, USA.<br /><searchLink fieldCode="AU" term="%22Park+IH%22">Park IH</searchLink>; Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, 06520, USA. inhyun.park@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jan 20; Vol. 13 (1), pp. 430. <i>Date of Electronic Publication: </i>2022 Jan 20.
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