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Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.

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Title: Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
Authors: Kandasamy P; Wave Life Sciences, Cambridge, MA, USA., McClorey G; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK., Shimizu M; Wave Life Sciences, Cambridge, MA, USA., Kothari N; Wave Life Sciences, Cambridge, MA, USA., Alam R; Wave Life Sciences, Cambridge, MA, USA., Iwamoto N; Wave Life Sciences, Cambridge, MA, USA., Kumarasamy J; Wave Life Sciences, Cambridge, MA, USA., Bommineni GR; Wave Life Sciences, Cambridge, MA, USA., Bezigian A; Wave Life Sciences, Cambridge, MA, USA., Chivatakarn O; Wave Life Sciences, Cambridge, MA, USA., Butler DCD; Wave Life Sciences, Cambridge, MA, USA., Byrne M; Wave Life Sciences, Cambridge, MA, USA., Chwalenia K; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK., Davies KE; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK., Desai J; Wave Life Sciences, Cambridge, MA, USA., Shelke JD; Wave Life Sciences, Cambridge, MA, USA., Durbin AF; Wave Life Sciences, Cambridge, MA, USA., Ellerington R; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK., Edwards B; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK., Godfrey J; Wave Life Sciences, Cambridge, MA, USA., Hoss A; Wave Life Sciences, Cambridge, MA, USA., Liu F; Wave Life Sciences, Cambridge, MA, USA., Longo K; Wave Life Sciences, Cambridge, MA, USA.; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford OX2 9DU, UK., Lu G; Wave Life Sciences, Cambridge, MA, USA., Marappan S; Wave Life Sciences, Cambridge, MA, USA., Oieni J; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK., Paik IH; Wave Life Sciences, Cambridge, MA, USA., Estabrook EP; Wave Life Sciences, Cambridge, MA, USA., Shivalila C; Wave Life Sciences, Cambridge, MA, USA., Tischbein M; Wave Life Sciences, Cambridge, MA, USA., Kawamoto T; Wave Life Sciences, Cambridge, MA, USA., Rinaldi C; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford OX2 9DU, UK., Rajão-Saraiva J; Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK., Tripathi S; Wave Life Sciences, Cambridge, MA, USA., Yang H; Wave Life Sciences, Cambridge, MA, USA., Yin Y; Wave Life Sciences, Cambridge, MA, USA., Zhao X; Wave Life Sciences, Cambridge, MA, USA., Zhou C; Wave Life Sciences, Cambridge, MA, USA., Zhang J; Wave Life Sciences, Cambridge, MA, USA., Apponi L; Wave Life Sciences, Cambridge, MA, USA., Wood MJA; Department of Paediatrics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford OX2 9DU, UK., Vargeese C; Wave Life Sciences, Cambridge, MA, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2022 Jun 10; Vol. 50 (10), pp. 5443-5466.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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