Comparative Immunogenicity of the Recombinant Receptor-Binding Domain of Protein S SARS-CoV-2 Obtained in Prokaryotic and Mammalian Expression Systems.

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Title: Comparative Immunogenicity of the Recombinant Receptor-Binding Domain of Protein S SARS-CoV-2 Obtained in Prokaryotic and Mammalian Expression Systems.
Authors: Merkuleva IA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Shcherbakov DN; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Borgoyakova MB; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Shanshin DV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Rudometov AP; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Karpenko LI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Belenkaya SV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Isaeva AA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Nesmeyanova VS; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Kazachinskaia EI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Volosnikova EA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Esina TI; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Zaykovskaya AV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Pyankov OV; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia., Borisevich SS; Laboratory of Chemical Physics, Ufa Institute of Chemistry, Ufa Federal Research Center, 450078 Ufa, Russia., Shelemba AA; Federal Research Center of Fundamental and Translational Medicine, 630060 Novosibirsk, Russia., Chikaev AN; Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia., Ilyichev AA; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.
Source: Vaccines [Vaccines (Basel)] 2022 Jan 09; Vol. 10 (1). Date of Electronic Publication: 2022 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE
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  Data: Comparative Immunogenicity of the Recombinant Receptor-Binding Domain of Protein S SARS-CoV-2 Obtained in Prokaryotic and Mammalian Expression Systems.
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  Data: <searchLink fieldCode="AU" term="%22Merkuleva+IA%22">Merkuleva IA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Shcherbakov+DN%22">Shcherbakov DN</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Borgoyakova+MB%22">Borgoyakova MB</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Shanshin+DV%22">Shanshin DV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Rudometov+AP%22">Rudometov AP</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Karpenko+LI%22">Karpenko LI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Belenkaya+SV%22">Belenkaya SV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Isaeva+AA%22">Isaeva AA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Nesmeyanova+VS%22">Nesmeyanova VS</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Kazachinskaia+EI%22">Kazachinskaia EI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Volosnikova+EA%22">Volosnikova EA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Esina+TI%22">Esina TI</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Zaykovskaya+AV%22">Zaykovskaya AV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Pyankov+OV%22">Pyankov OV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Borisevich+SS%22">Borisevich SS</searchLink>; Laboratory of Chemical Physics, Ufa Institute of Chemistry, Ufa Federal Research Center, 450078 Ufa, Russia.<br /><searchLink fieldCode="AU" term="%22Shelemba+AA%22">Shelemba AA</searchLink>; Federal Research Center of Fundamental and Translational Medicine, 630060 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Chikaev+AN%22">Chikaev AN</searchLink>; Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.<br /><searchLink fieldCode="AU" term="%22Ilyichev+AA%22">Ilyichev AA</searchLink>; State Research Center of Virology and Biotechnology 'Vector', Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Novosibirsk, Russia.
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  Data: <searchLink fieldCode="JN" term="%22101629355%22">Vaccines</searchLink> [Vaccines (Basel)] 2022 Jan 09; Vol. 10 (1). <i>Date of Electronic Publication: </i>2022 Jan 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101629355 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2076-393X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222076393X%22">2076393X </searchLink><i>NLM ISO Abbreviation: </i>Vaccines (Basel) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/vaccines10010096
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