Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.

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Title: Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.
Authors: Chhatwal JP; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. Electronic address: chhatwal.jasmeer@mgh.harvard.edu., Schultz SA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA., McDade E; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Schultz AP; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA., Liu L; Department of Neurology, Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Hanseeuw BJ; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Université Catholique de Louvain, Brussels, Belgium., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Feldman R; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Fitzpatrick CD; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Sparks KP; Massachusetts General Hospital, Boston, MA, USA., Levin J; Department of Neurology, Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany., Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Renton AE; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Esposito BT; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fernandez MV; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Sung YJ; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Lee JH; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Klunk WE; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Hofmann A; German Center for Neurodegenerative Disease, Tübingen, Germany., Noble JM; Columbia University Irving Medical Center, Department of Neurology, New York, NY, USA., Graff-Radford N; Mayo Clinic, Department of Neurology, Jacksonville, FL, USA., Mori H; Osaka City University, Sumiyoshi Ward, Osaka, Japan., Salloway SM; Butler Hospital, Memory and Aging Program, Brown University Alpert Medical School, Providence, RI, USA., Masters CL; The University of Melbourne, Melbourne, VIC, Australia; Florey Institute, Melbourne, VIC, Australia., Martins R; Department of Biomedical Sciences, Macquarie University, Sydney, NSW, Australia., Karch CM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Xiong C; Division of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Cruchaga C; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Perrin RJ; Department of Pathology, Washington University in St Louis, St Louis, MO, USA., Gordon BA; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Fox NC; UCL Queen Square Institute of Neurology, Dementia Research Centre, London, UK., Schofield PR; Neuroscience Research Australia, Sydney, NSW, Australia; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia., Fagan AM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Goate AM; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Morris JC; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Bateman RJ; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Johnson KA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Sperling RA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.
Corporate Authors: Dominantly Inherited Alzheimer's Network Investigators
Source: The Lancet. Neurology [Lancet Neurol] 2022 Feb; Vol. 21 (2), pp. 140-152.
Publication Type: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-4465
DOI:10.1016/S1474-4422(21)00375-6