Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.
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| Title: | Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. |
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| Authors: | Chhatwal JP; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. Electronic address: chhatwal.jasmeer@mgh.harvard.edu., Schultz SA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA., McDade E; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Schultz AP; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA., Liu L; Department of Neurology, Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Hanseeuw BJ; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Université Catholique de Louvain, Brussels, Belgium., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Feldman R; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Fitzpatrick CD; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Sparks KP; Massachusetts General Hospital, Boston, MA, USA., Levin J; Department of Neurology, Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany., Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Renton AE; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Esposito BT; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fernandez MV; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Sung YJ; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Lee JH; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Klunk WE; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Hofmann A; German Center for Neurodegenerative Disease, Tübingen, Germany., Noble JM; Columbia University Irving Medical Center, Department of Neurology, New York, NY, USA., Graff-Radford N; Mayo Clinic, Department of Neurology, Jacksonville, FL, USA., Mori H; Osaka City University, Sumiyoshi Ward, Osaka, Japan., Salloway SM; Butler Hospital, Memory and Aging Program, Brown University Alpert Medical School, Providence, RI, USA., Masters CL; The University of Melbourne, Melbourne, VIC, Australia; Florey Institute, Melbourne, VIC, Australia., Martins R; Department of Biomedical Sciences, Macquarie University, Sydney, NSW, Australia., Karch CM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Xiong C; Division of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Cruchaga C; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA., Perrin RJ; Department of Pathology, Washington University in St Louis, St Louis, MO, USA., Gordon BA; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA., Fox NC; UCL Queen Square Institute of Neurology, Dementia Research Centre, London, UK., Schofield PR; Neuroscience Research Australia, Sydney, NSW, Australia; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia., Fagan AM; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Goate AM; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Morris JC; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Bateman RJ; Department of Neurology, Washington University in St Louis, St Louis, MO, USA., Johnson KA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA., Sperling RA; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. |
| Corporate Authors: | Dominantly Inherited Alzheimer's Network Investigators |
| Source: | The Lancet. Neurology [Lancet Neurol] 2022 Feb; Vol. 21 (2), pp. 140-152. |
| Publication Type: | Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 35065037 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chhatwal+JP%22">Chhatwal JP</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. Electronic address: chhatwal.jasmeer@mgh.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Schultz+SA%22">Schultz SA</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McDade+E%22">McDade E</searchLink>; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Schultz+AP%22">Schultz AP</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hanseeuw+BJ%22">Hanseeuw BJ</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Université Catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Joseph-Mathurin+N%22">Joseph-Mathurin N</searchLink>; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Feldman+R%22">Feldman R</searchLink>; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+CD%22">Fitzpatrick CD</searchLink>; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sparks+KP%22">Sparks KP</searchLink>; Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Levin+J%22">Levin J</searchLink>; Department of Neurology, Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Berman+SB%22">Berman SB</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Renton+AE%22">Renton AE</searchLink>; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Esposito+BT%22">Esposito BT</searchLink>; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez+MV%22">Fernandez MV</searchLink>; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Sung+YJ%22">Sung YJ</searchLink>; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Klunk+WE%22">Klunk WE</searchLink>; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hofmann+A%22">Hofmann A</searchLink>; German Center for Neurodegenerative Disease, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Noble+JM%22">Noble JM</searchLink>; Columbia University Irving Medical Center, Department of Neurology, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Graff-Radford+N%22">Graff-Radford N</searchLink>; Mayo Clinic, Department of Neurology, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mori+H%22">Mori H</searchLink>; Osaka City University, Sumiyoshi Ward, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Salloway+SM%22">Salloway SM</searchLink>; Butler Hospital, Memory and Aging Program, Brown University Alpert Medical School, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Masters+CL%22">Masters CL</searchLink>; The University of Melbourne, Melbourne, VIC, Australia; Florey Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Martins+R%22">Martins R</searchLink>; Department of Biomedical Sciences, Macquarie University, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Karch+CM%22">Karch CM</searchLink>; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Xiong+C%22">Xiong C</searchLink>; Division of Biostatistics, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Perrin+RJ%22">Perrin RJ</searchLink>; Department of Pathology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Mallinckrodt Institute of Radiology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Fox+NC%22">Fox NC</searchLink>; UCL Queen Square Institute of Neurology, Dementia Research Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Schofield+PR%22">Schofield PR</searchLink>; Neuroscience Research Australia, Sydney, NSW, Australia; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Fagan+AM%22">Fagan AM</searchLink>; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Goate+AM%22">Goate AM</searchLink>; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; Department of Neurology, Washington University in St Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+KA%22">Johnson KA</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sperling+RA%22">Sperling RA</searchLink>; Department of Neurology, Harvard Medical School, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Dominantly+Inherited+Alzheimer's+Network+Investigators%22">Dominantly Inherited Alzheimer's Network Investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101139309%22">The Lancet. Neurology</searchLink> [Lancet Neurol] 2022 Feb; Vol. 21 (2), pp. 140-152. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lancet+Pub%2E+Group%22">Lancet Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101139309 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-4465 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214744422%22">14744422 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Neurol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35065037 |
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