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Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.

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Title: Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.
Authors: Bognàr T; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands. Electronic address: t.bognar-2@umcutrecht.nl., Bartelink IH; Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands., Egberts TCG; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands., Rademaker CMA; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands., Versluys AB; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Slatter MA; Paediatric Haematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne, United Kingdom & Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Kletzel M; Stem Cell Transplant Program, Ann & Robert Lurie Children's Hospital/Northwestern University, Chicago, Illinois., Nath CE; Children's Hospital at Westmead, Sydney, New South Wales, Australia., Cuvelier GDE; Pediatric Blood and Marrow Transplantation, CancerCare Manitoba, University of Manitoba, Winnipeg, Manitoba, Canada., Savic RM; Departments of Allergy/Immunology/Bone Marrow Transplantation, Clinical Pharmacy, or Bioengineering & Therapeutic Sciences of the University of California San Francisco (UCSF), San Francisco, California., Dvorak C; Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California., Long-Boyle JR; Department Clinical Pharmacy and Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California., Cowan MJ; Department Clinical Pharmacy and Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California., Bittencourt H; Transplant and Cell Therapy Program. Hematology-Oncology Division, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada., Bredius RGM; Department of Pediatrics, Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands., Güngör T; Division of Stem Cell Transplantation and Children`s Research Center (CRC), University Children`s hospital Zürich, Switzerland., Shaw PJ; Blood Transplant and Cell Therapies Program, The Children's Hospital at Westmead, Sydney, NSW Australia, Clinical Professor, Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Ansari M; Cansearch Research Platform in Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland., Hassan M; ECM, KFC, Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Krajinovic M; Centre de Cancérologie Charles-Bruneau Centre de recherche - Hôpital Sainte-Justine Montréal, Montréal, Québec, Canada., Hempel G; University of Münster, Münster, Germany., Marktel S; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy., Chiesa R; Great Ormond Street, Hospital for Children London, United Kingdom & Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy., Théoret Y; Clinical Pharmacology Laboratory, OPTILAB and Research Center, CHU Sainte-Justine Montréal, Montreal, Québec, Canada., Lund T; Division of Pediatric Blood and Marrow Transplantation, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minnesota., Orchard PJ; Division of Pediatric Blood and Marrow Transplantation, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minnesota., Wynn RF; The Royal Manchester Children's Hospital, Manchester, United Kingdom., Boelens JJ; Stem Cell Transplantation and Cellular Therapies, Memorial Sloan-Kettering Cancer Center, New York, New York., Lalmohamed A; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands.
Source: Transplantation and cellular therapy [Transplant Cell Ther] 2022 Apr; Vol. 28 (4), pp. 196-202. Date of Electronic Publication: 2022 Jan 19.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101774629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6367 (Electronic) Linking ISSN: 26666367 NLM ISO Abbreviation: Transplant Cell Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.
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  Data: <searchLink fieldCode="AU" term="%22Bognàr+T%22">Bognàr T</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands. Electronic address: t.bognar-2@umcutrecht.nl.<br /><searchLink fieldCode="AU" term="%22Bartelink+IH%22">Bartelink IH</searchLink>; Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Egberts+TCG%22">Egberts TCG</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rademaker+CMA%22">Rademaker CMA</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Versluys+AB%22">Versluys AB</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Slatter+MA%22">Slatter MA</searchLink>; Paediatric Haematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne, United Kingdom & Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kletzel+M%22">Kletzel M</searchLink>; Stem Cell Transplant Program, Ann & Robert Lurie Children's Hospital/Northwestern University, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Nath+CE%22">Nath CE</searchLink>; Children's Hospital at Westmead, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Cuvelier+GDE%22">Cuvelier GDE</searchLink>; Pediatric Blood and Marrow Transplantation, CancerCare Manitoba, University of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Savic+RM%22">Savic RM</searchLink>; Departments of Allergy/Immunology/Bone Marrow Transplantation, Clinical Pharmacy, or Bioengineering & Therapeutic Sciences of the University of California San Francisco (UCSF), San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Dvorak+C%22">Dvorak C</searchLink>; Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Long-Boyle+JR%22">Long-Boyle JR</searchLink>; Department Clinical Pharmacy and Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Cowan+MJ%22">Cowan MJ</searchLink>; Department Clinical Pharmacy and Division of Pediatric Allergy/Immunology/Bone Marrow Transplantation, University of California San Francisco (UCSF), San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Bittencourt+H%22">Bittencourt H</searchLink>; Transplant and Cell Therapy Program. Hematology-Oncology Division, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Bredius+RGM%22">Bredius RGM</searchLink>; Department of Pediatrics, Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Güngör+T%22">Güngör T</searchLink>; Division of Stem Cell Transplantation and Children`s Research Center (CRC), University Children`s hospital Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Shaw+PJ%22">Shaw PJ</searchLink>; Blood Transplant and Cell Therapies Program, The Children's Hospital at Westmead, Sydney, NSW Australia, Clinical Professor, Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ansari+M%22">Ansari M</searchLink>; Cansearch Research Platform in Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hassan+M%22">Hassan M</searchLink>; ECM, KFC, Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Krajinovic+M%22">Krajinovic M</searchLink>; Centre de Cancérologie Charles-Bruneau Centre de recherche - Hôpital Sainte-Justine Montréal, Montréal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Hempel+G%22">Hempel G</searchLink>; University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Marktel+S%22">Marktel S</searchLink>; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiesa+R%22">Chiesa R</searchLink>; Great Ormond Street, Hospital for Children London, United Kingdom & Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Théoret+Y%22">Théoret Y</searchLink>; Clinical Pharmacology Laboratory, OPTILAB and Research Center, CHU Sainte-Justine Montréal, Montreal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Lund+T%22">Lund T</searchLink>; Division of Pediatric Blood and Marrow Transplantation, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Orchard+PJ%22">Orchard PJ</searchLink>; Division of Pediatric Blood and Marrow Transplantation, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Wynn+RF%22">Wynn RF</searchLink>; The Royal Manchester Children's Hospital, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boelens+JJ%22">Boelens JJ</searchLink>; Stem Cell Transplantation and Cellular Therapies, Memorial Sloan-Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Lalmohamed+A%22">Lalmohamed A</searchLink>; Department of Clinical Pharmacy, University Medical Center Utrecht/Wilhelmina Children's Hospital, Utrecht, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101774629%22">Transplantation and cellular therapy</searchLink> [Transplant Cell Ther] 2022 Apr; Vol. 28 (4), pp. 196-202. <i>Date of Electronic Publication: </i>2022 Jan 19.
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