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Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.

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Title: Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.
Authors: Perkins GD; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Ji C; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Connolly BA; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland.; Lane Fox Clinical Respiratory Physiology Research Centre, Guy's and St Thomas' NHS Foundation Trust, London, England.; Centre for Human and Applied Physiological Sciences, King's College London, London, England.; Department of Physiotherapy, University of Melbourne, Melbourne, Australia., Couper K; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Lall R; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Baillie JK; Roslin Institute, University of Edinburgh, Midlothian, Scotland.; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, Scotland., Bradley JM; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland., Dark P; NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, England.; Salford Royal Hospital, Northern Care Alliance NHS Group, Manchester, England., Dave C; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., De Soyza A; Population and Health Science Institute, NIHR Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England., Dennis AV; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Devrell A; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; Research Champion Team, West Midlands Clinical Research Network, Wolverhampton, England., Fairbairn S; Grange University Hospital, Aneurin Bevan University Health Board, Cwmbran, Wales., Ghani H; Watford General Hospital, West Hertfordshire Hospitals NHS Trust, Watford, England., Gorman EA; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland., Green CA; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Hart N; Lane Fox Clinical Respiratory Physiology Research Centre, Guy's and St Thomas' NHS Foundation Trust, London, England.; Centre for Human and Applied Physiological Sciences, King's College London, London, England., Hee SW; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, England., Kimbley Z; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Madathil S; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., McGowan N; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Messer B; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England., Naisbitt J; Fairfield General Hospital, Pennine Acute Hospitals NHS Trust, Northern Care Alliance NHS Group, Bury, England., Norman C; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Parekh D; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England.; Institute of Inflammation and Ageing, School of Medical and Dental Sciences, University of Birmingham, Birmingham, England., Parkin EM; Fairfield General Hospital, Pennine Acute Hospitals NHS Trust, Northern Care Alliance NHS Group, Bury, England., Patel J; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England.; Institute of Inflammation and Ageing, School of Medical and Dental Sciences, University of Birmingham, Birmingham, England., Regan SE; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Ross C; Imperial College Healthcare NHS Trust, London, England., Rostron AJ; Sunderland Royal Hospital, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, England.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, England., Saim M; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., Simonds AK; Royal Brompton and Harefield Hospital, Guy's and St Thomas' NHS Foundation Trust, London, England., Skilton E; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England., Stallard N; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, England., Steiner M; Institute for Lung Health, NIHR Leicester Biomedical Research Centre, Department of Respiratory Sciences, University of Leicester, Leicester, England., Vancheeswaran R; Watford General Hospital, West Hertfordshire Hospitals NHS Trust, Watford, England., Yeung J; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, England.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, England., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland.; Royal Victoria Hospital, Belfast, Northern Ireland.
Corporate Authors: RECOVERY-RS Collaborators
Source: JAMA [JAMA] 2022 Feb 08; Vol. 327 (6), pp. 546-558.
Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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