Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology.
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| Title: | Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology. |
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| Authors: | Braun DJ; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America., Powell DK; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, Kentucky, United States of America., McLouth CJ; Department of Behavioral Science, University of Kentucky, Lexington, Kentucky, United States of America., Roy SM; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America., Watterson DM; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America., Van Eldik LJ; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America. |
| Source: | PloS one [PLoS One] 2022 Jan 26; Vol. 17 (1), pp. e0262474. Date of Electronic Publication: 2022 Jan 26 (Print Publication: 2022). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0262474 |
