Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology.
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| Title: | Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology. |
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| Authors: | Braun DJ; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America., Powell DK; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, Kentucky, United States of America., McLouth CJ; Department of Behavioral Science, University of Kentucky, Lexington, Kentucky, United States of America., Roy SM; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America., Watterson DM; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America., Van Eldik LJ; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America. |
| Source: | PloS one [PLoS One] 2022 Jan 26; Vol. 17 (1), pp. e0262474. Date of Electronic Publication: 2022 Jan 26 (Print Publication: 2022). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 35081152 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Braun+DJ%22">Braun DJ</searchLink>; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Powell+DK%22">Powell DK</searchLink>; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Magnetic Resonance Imaging and Spectroscopy Center, University of Kentucky, Lexington, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22McLouth+CJ%22">McLouth CJ</searchLink>; Department of Behavioral Science, University of Kentucky, Lexington, Kentucky, United States of America.<br /><searchLink fieldCode="AU" term="%22Roy+SM%22">Roy SM</searchLink>; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Watterson+DM%22">Watterson DM</searchLink>; Department of Pharmacology, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Van+Eldik+LJ%22">Van Eldik LJ</searchLink>; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America.; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2022 Jan 26; Vol. 17 (1), pp. e0262474. <i>Date of Electronic Publication: </i>2022 Jan 26 (<i>Print Publication: </i>2022). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35081152 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pone.0262474 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0262474 Titles: – TitleFull: Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Braun DJ – PersonEntity: Name: NameFull: Powell DK – PersonEntity: Name: NameFull: McLouth CJ – PersonEntity: Name: NameFull: Roy SM – PersonEntity: Name: NameFull: Watterson DM – PersonEntity: Name: NameFull: Van Eldik LJ IsPartOfRelationships: – BibEntity: Dates: – D: 26 M: 01 Text: 2022 Jan 26 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1932-6203 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: PloS one Type: main |
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