Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma.

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Title: Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma.
Authors: Sakemura R; T Cell Engineering.; Division of Hematology., Hefazi M; T Cell Engineering.; Division of Hematology., Siegler EL; T Cell Engineering.; Division of Hematology., Cox MJ; T Cell Engineering.; Division of Hematology., Larson DP; Division of Hematopathology., Hansen MJ; Department of Immunology., Manriquez Roman C; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences.; Department of Molecular Medicine., Schick KJ; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences.; Department of Molecular Pharmacology and Experimental Therapeutics, and., Can I; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences., Tapper EE; T Cell Engineering.; Division of Hematology., Horvei P; T Cell Engineering., Adada MM; T Cell Engineering.; Division of Hematology., Bezerra ED; T Cell Engineering.; Division of Hematology., Kankeu Fonkoua LA; T Cell Engineering.; Division of Hematology., Ruff MW; T Cell Engineering.; Department of Neurology, Mayo Clinic, Rochester, MN; and., Nevala WK; Department of Immunology., Walters DK; Department of Immunology., Parikh SA; Division of Hematology., Lin Y; Division of Hematology., Jelinek DF; Department of Immunology., Kay NE; Division of Hematology., Bergsagel PL; Department of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ., Kenderian SS; T Cell Engineering.; Division of Hematology.; Department of Immunology.; Department of Molecular Medicine.
Source: Blood [Blood] 2022 Jun 30; Vol. 139 (26), pp. 3708-3721.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma.
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  Data: <searchLink fieldCode="AU" term="%22Sakemura+R%22">Sakemura R</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Hefazi+M%22">Hefazi M</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Siegler+EL%22">Siegler EL</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Cox+MJ%22">Cox MJ</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Larson+DP%22">Larson DP</searchLink>; Division of Hematopathology.<br /><searchLink fieldCode="AU" term="%22Hansen+MJ%22">Hansen MJ</searchLink>; Department of Immunology.<br /><searchLink fieldCode="AU" term="%22Manriquez+Roman+C%22">Manriquez Roman C</searchLink>; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences.; Department of Molecular Medicine.<br /><searchLink fieldCode="AU" term="%22Schick+KJ%22">Schick KJ</searchLink>; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences.; Department of Molecular Pharmacology and Experimental Therapeutics, and.<br /><searchLink fieldCode="AU" term="%22Can+I%22">Can I</searchLink>; T Cell Engineering.; Division of Hematology.; Mayo Clinic Graduate School of Biomedical Sciences.<br /><searchLink fieldCode="AU" term="%22Tapper+EE%22">Tapper EE</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Horvei+P%22">Horvei P</searchLink>; T Cell Engineering.<br /><searchLink fieldCode="AU" term="%22Adada+MM%22">Adada MM</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Bezerra+ED%22">Bezerra ED</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Kankeu+Fonkoua+LA%22">Kankeu Fonkoua LA</searchLink>; T Cell Engineering.; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Ruff+MW%22">Ruff MW</searchLink>; T Cell Engineering.; Department of Neurology, Mayo Clinic, Rochester, MN; and.<br /><searchLink fieldCode="AU" term="%22Nevala+WK%22">Nevala WK</searchLink>; Department of Immunology.<br /><searchLink fieldCode="AU" term="%22Walters+DK%22">Walters DK</searchLink>; Department of Immunology.<br /><searchLink fieldCode="AU" term="%22Parikh+SA%22">Parikh SA</searchLink>; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Jelinek+DF%22">Jelinek DF</searchLink>; Department of Immunology.<br /><searchLink fieldCode="AU" term="%22Kay+NE%22">Kay NE</searchLink>; Division of Hematology.<br /><searchLink fieldCode="AU" term="%22Bergsagel+PL%22">Bergsagel PL</searchLink>; Department of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ.<br /><searchLink fieldCode="AU" term="%22Kenderian+SS%22">Kenderian SS</searchLink>; T Cell Engineering.; Division of Hematology.; Department of Immunology.; Department of Molecular Medicine.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2022 Jun 30; Vol. 139 (26), pp. 3708-3721.
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        Value: 10.1182/blood.2021012811
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