View in EDS

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.

Saved in:
Bibliographic Details
Title: Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
Authors: Cherney EC; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lo J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Huynh T; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Wei D; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ahuja V; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Quesnelle C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schieven GL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Futran A; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Locke GA; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lin Z; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Monereau L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Chaudhry C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Blum J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li S; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fereshteh M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li-Wang B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Gangwar S; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Pan C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Chong C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Zhu X; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Posy SL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Sack JS; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang P; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ruzanov M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Harner M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Akhtar F; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schroeder GM; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Vite G; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fink B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
Source: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3518-3538. Date of Electronic Publication: 2022 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 35108011
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Cherney+EC%22">Cherney EC</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Lo+J%22">Lo J</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Huynh+T%22">Huynh T</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Wei+D%22">Wei D</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Ahuja+V%22">Ahuja V</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Quesnelle+C%22">Quesnelle C</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Schieven+GL%22">Schieven GL</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Futran+A%22">Futran A</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Locke+GA%22">Locke GA</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Monereau+L%22">Monereau L</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Chaudhry+C%22">Chaudhry C</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Blum+J%22">Blum J</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Fereshteh+M%22">Fereshteh M</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Li-Wang+B%22">Li-Wang B</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Gangwar+S%22">Gangwar S</searchLink>; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Pan+C%22">Pan C</searchLink>; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Chong+C%22">Chong C</searchLink>; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Posy+SL%22">Posy SL</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Sack+JS%22">Sack JS</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Ruzanov+M%22">Ruzanov M</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Harner+M%22">Harner M</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Akhtar+F%22">Akhtar F</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Schroeder+GM%22">Schroeder GM</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Vite+G%22">Vite G</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Fink+B%22">Fink B</searchLink>; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3518-3538. <i>Date of Electronic Publication: </i>2022 Feb 02.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35108011
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acs.jmedchem.1c01986
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3518
    Titles:
      – TitleFull: Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Cherney EC
      – PersonEntity:
          Name:
            NameFull: Zhang L
      – PersonEntity:
          Name:
            NameFull: Lo J
      – PersonEntity:
          Name:
            NameFull: Huynh T
      – PersonEntity:
          Name:
            NameFull: Wei D
      – PersonEntity:
          Name:
            NameFull: Ahuja V
      – PersonEntity:
          Name:
            NameFull: Quesnelle C
      – PersonEntity:
          Name:
            NameFull: Schieven GL
      – PersonEntity:
          Name:
            NameFull: Futran A
      – PersonEntity:
          Name:
            NameFull: Locke GA
      – PersonEntity:
          Name:
            NameFull: Lin Z
      – PersonEntity:
          Name:
            NameFull: Monereau L
      – PersonEntity:
          Name:
            NameFull: Chaudhry C
      – PersonEntity:
          Name:
            NameFull: Blum J
      – PersonEntity:
          Name:
            NameFull: Li S
      – PersonEntity:
          Name:
            NameFull: Fereshteh M
      – PersonEntity:
          Name:
            NameFull: Li-Wang B
      – PersonEntity:
          Name:
            NameFull: Gangwar S
      – PersonEntity:
          Name:
            NameFull: Pan C
      – PersonEntity:
          Name:
            NameFull: Chong C
      – PersonEntity:
          Name:
            NameFull: Zhu X
      – PersonEntity:
          Name:
            NameFull: Posy SL
      – PersonEntity:
          Name:
            NameFull: Sack JS
      – PersonEntity:
          Name:
            NameFull: Zhang P
      – PersonEntity:
          Name:
            NameFull: Ruzanov M
      – PersonEntity:
          Name:
            NameFull: Harner M
      – PersonEntity:
          Name:
            NameFull: Akhtar F
      – PersonEntity:
          Name:
            NameFull: Schroeder GM
      – PersonEntity:
          Name:
            NameFull: Vite G
      – PersonEntity:
          Name:
            NameFull: Fink B
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 02
              Text: 2022 Feb 24
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1520-4804
          Numbering:
            – Type: volume
              Value: 65
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Journal of medicinal chemistry
              Type: main
ResultId 1