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Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1.

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Title: Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1.
Authors: Durr AJ; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia., Hathaway QA; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia., Kunovac A; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia., Taylor AD; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia., Pinti MV; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; West Virginia University School of Pharmacy, Morgantown, West Virginia.; Department of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia., Rizwan S; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia., Shepherd DL; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia., Cook CC; Cardiovascular and Thoracic Surgery, West Virginia University School of Medicine, Morgantown, West Virginia., Fink GK; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia., Hollander JM; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia.
Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2022 Mar 01; Vol. 322 (3), pp. C482-C495. Date of Electronic Publication: 2022 Feb 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot1.
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  Data: <searchLink fieldCode="AU" term="%22Durr+AJ%22">Durr AJ</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Hathaway+QA%22">Hathaway QA</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Kunovac+A%22">Kunovac A</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Taylor+AD%22">Taylor AD</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Pinti+MV%22">Pinti MV</searchLink>; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; West Virginia University School of Pharmacy, Morgantown, West Virginia.; Department of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Rizwan+S%22">Rizwan S</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Shepherd+DL%22">Shepherd DL</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Cook+CC%22">Cook CC</searchLink>; Cardiovascular and Thoracic Surgery, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Fink+GK%22">Fink GK</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.<br /><searchLink fieldCode="AU" term="%22Hollander+JM%22">Hollander JM</searchLink>; Division of Exercise Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.; Mitochondria, Metabolism & Bioenergetics Working Group, West Virginia University School of Medicine, Morgantown, West Virginia.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, West Virginia.
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