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Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.

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Title: Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
Authors: Gruijs da Silva LA; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany., Simonetti F; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Hutten S; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany., Riemenschneider H; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Sternburg EL; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany., Pietrek LM; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany., Gebel J; Institute for Biophysical Chemistry, Goethe-Universität, Frankfurt am Main, Germany., Dötsch V; Institute for Biophysical Chemistry, Goethe-Universität, Frankfurt am Main, Germany., Edbauer D; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany., Hummer G; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Institute for Biophysics, Goethe-Universität, Frankfurt am Main, Germany., Stelzl LS; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; KOMET1, Institute of Physics, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany., Dormann D; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.
Source: The EMBO journal [EMBO J] 2022 Apr 19; Vol. 41 (8), pp. e108443. Date of Electronic Publication: 2022 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
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  Data: <searchLink fieldCode="AU" term="%22Gruijs+da+Silva+LA%22">Gruijs da Silva LA</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Simonetti+F%22">Simonetti F</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hutten+S%22">Hutten S</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Riemenschneider+H%22">Riemenschneider H</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sternburg+EL%22">Sternburg EL</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Pietrek+LM%22">Pietrek LM</searchLink>; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Gebel+J%22">Gebel J</searchLink>; Institute for Biophysical Chemistry, Goethe-Universität, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Dötsch+V%22">Dötsch V</searchLink>; Institute for Biophysical Chemistry, Goethe-Universität, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Edbauer+D%22">Edbauer D</searchLink>; Graduate School of Systemic Neurosciences (GSN), Planegg-Martinsried, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hummer+G%22">Hummer G</searchLink>; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; Institute for Biophysics, Goethe-Universität, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Stelzl+LS%22">Stelzl LS</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.; KOMET1, Institute of Physics, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Dormann+D%22">Dormann D</searchLink>; Biocenter, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.
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