Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
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| Title: | Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. |
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| Authors: | Shen M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Wei Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Kim H; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Princeton University Small Molecule Screening Center, Princeton University, Princeton, NJ, USA., Wan L; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Jiang YZ; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China., Hang X; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Raba M; Crelux GmgH, Martinsried, Germany., Remiszewski S; SWR Pharma Consulting LLC, Princeton, NJ, USA., Rowicki M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Wu CG; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA., Wu S; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China., Zhang L; Department of Pathology, University Medical Center of Princeton, Plainsboro, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Lu X; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Yuan M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Smith HA; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Zheng A; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA., Bertino J; Pharmacokinetics and Pharmacodynamics (PK/PD) Shared Resource, Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.; Robert Wood Johnson Medical School Rutgers, The State University of New Jersey, New Brunswick, NJ, USA., Jin JF; Firebrand Therapeutics, Princeton, NJ, USA., Xing Y; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA., Shao ZM; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, P.R. China., Kang Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. ykang@princeton.edu.; Cancer Metabolism and Growth Program, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA. ykang@princeton.edu.; Ludwig Institute for Cancer Research Princeton Branch, Princeton, NJ, USA. ykang@princeton.edu. |
| Source: | Nature cancer [Nat Cancer] 2022 Jan; Vol. 3 (1), pp. 43-59. Date of Electronic Publication: 2021 Nov 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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