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Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer.

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Title: Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer.
Authors: Shen M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Smith HA; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Wei Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Jiang YZ; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China., Zhao S; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China., Wang N; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Rowicki M; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Tang Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Hang X; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Wu S; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China., Wan L; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Shao ZM; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China., Kang Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. ykang@princeton.edu.; Cancer Metabolism and Growth Program, The Cancer Institute of New Jersey, New Brunswick, NJ, USA. ykang@princeton.edu.; Ludwig Institute for Cancer Research Princeton Branch, Princeton, NJ, USA. ykang@princeton.edu.
Source: Nature cancer [Nat Cancer] 2022 Jan; Vol. 3 (1), pp. 60-74. Date of Electronic Publication: 2021 Nov 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Smith+HA%22">Smith HA</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wei+Y%22">Wei Y</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+YZ%22">Jiang YZ</searchLink>; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Rowicki+M%22">Rowicki M</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Hang+X%22">Hang X</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wan+L%22">Wan L</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Shao+ZM%22">Shao ZM</searchLink>; Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Kang+Y%22">Kang Y</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. ykang@princeton.edu.; Cancer Metabolism and Growth Program, The Cancer Institute of New Jersey, New Brunswick, NJ, USA. ykang@princeton.edu.; Ludwig Institute for Cancer Research Princeton Branch, Princeton, NJ, USA. ykang@princeton.edu.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2022 Jan; Vol. 3 (1), pp. 60-74. <i>Date of Electronic Publication: </i>2021 Nov 29.
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