Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.

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Title: Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.
Authors: Fraszczyk E; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Spijkerman AMW; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Zhang Y; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany., Brandmaier S; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Day FR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zhou L; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Wackers P; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Dollé MET; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Bloks VW; Department of Pediatrics, Section of Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gào X; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Kooner J; Department of Cardiology, Ealing Hospital, Ealing, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Kriebel J; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Picavet HSJ; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Rathmann W; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Biometrics and Epidemiology, German Diabetes Center, Auf'm Hennekamp, Duesseldorf, Germany., Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Loh M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Verschuren WMM; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., van Vliet-Ostaptchouk JV; Genomics Coordination Center, Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Department of Paediatrics, University of Cambridge School of Clinical Medicine, Cambridge, UK., Grallert H; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Luijten M; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. mirjam.luijten@rivm.nl., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. h.snieder@umcg.nl.
Source: Diabetologia [Diabetologia] 2022 May; Vol. 65 (5), pp. 763-776. Date of Electronic Publication: 2022 Feb 15.
Publication Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
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  Data: Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.
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  Data: <searchLink fieldCode="AU" term="%22Fraszczyk+E%22">Fraszczyk E</searchLink>; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Spijkerman+AMW%22">Spijkerman AMW</searchLink>; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Brandmaier+S%22">Brandmaier S</searchLink>; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Day+FR%22">Day FR</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wackers+P%22">Wackers P</searchLink>; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dollé+MET%22">Dollé MET</searchLink>; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bloks+VW%22">Bloks VW</searchLink>; Department of Pediatrics, Section of Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gào+X%22">Gào X</searchLink>; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gieger+C%22">Gieger C</searchLink>; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kooner+J%22">Kooner J</searchLink>; Department of Cardiology, Ealing Hospital, Ealing, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kriebel+J%22">Kriebel J</searchLink>; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Picavet+HSJ%22">Picavet HSJ</searchLink>; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rathmann+W%22">Rathmann W</searchLink>; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Biometrics and Epidemiology, German Diabetes Center, Auf'm Hennekamp, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Schöttker+B%22">Schöttker B</searchLink>; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Loh+M%22">Loh M</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Verschuren+WMM%22">Verschuren WMM</searchLink>; Centre for Nutrition, Prevention and Health services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Vliet-Ostaptchouk+JV%22">van Vliet-Ostaptchouk JV</searchLink>; Genomics Coordination Center, Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wareham+NJ%22">Wareham NJ</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+JC%22">Chambers JC</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ong+KK%22">Ong KK</searchLink>; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Department of Paediatrics, University of Cambridge School of Clinical Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Grallert+H%22">Grallert H</searchLink>; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Brenner+H%22">Brenner H</searchLink>; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Luijten+M%22">Luijten M</searchLink>; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. mirjam.luijten@rivm.nl.<br /><searchLink fieldCode="AU" term="%22Snieder+H%22">Snieder H</searchLink>; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. h.snieder@umcg.nl.
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