An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.
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| Title: | An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation. |
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| Authors: | Muik A; BioNTech SE, Mainz, Germany., Altintas I; Genmab, Utrecht, The Netherlands., Gieseke F; BioNTech SE, Mainz, Germany., Schoedel KB; BioNTech SE, Mainz, Germany., Burm SM; Genmab, Utrecht, The Netherlands., Toker A; BioNTech SE, Mainz, Germany., Salcedo TW; Genmab, Princeton, NJ, USA., Verzijl D; BioNTech SE, Mainz, Germany.; Genmab, Utrecht, The Netherlands.; Genmab, Princeton, NJ, USA.; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Eisel D; BioNTech SE, Mainz, Germany., Grunwitz C; BioNTech SE, Mainz, Germany., Kranz LM; BioNTech SE, Mainz, Germany., Vormehr M; BioNTech SE, Mainz, Germany., Satijn DPE; BioNTech SE, Mainz, Germany.; Genmab, Utrecht, The Netherlands.; Genmab, Princeton, NJ, USA.; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Diken M; BioNTech SE, Mainz, Germany., Kreiter S; BioNTech SE, Mainz, Germany., Sasser K; Genmab, Princeton, NJ, USA., Ahmadi T; BioNTech SE, Mainz, Germany.; Genmab, Utrecht, The Netherlands.; Genmab, Princeton, NJ, USA.; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Türeci Ö; BioNTech SE, Mainz, Germany., Breij ECW; Genmab, Utrecht, The Netherlands., Jure-Kunkel M; Genmab, Princeton, NJ, USA., Sahin U; BioNTech SE, Mainz, Germany.; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany. |
| Source: | Oncoimmunology [Oncoimmunology] 2022 Feb 16; Vol. 11 (1), pp. 2030135. Date of Electronic Publication: 2022 Feb 16 (Print Publication: 2022). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: eCollection Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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