RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study.
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| Title: | RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study. |
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| Authors: | Chauthe SK; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Sidduri P; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Reddy M; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Sistla R; Department of Medicinal Chemistry, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Byri V; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Uttaravalli MD; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Botlagunta M; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Kumar H; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Gupta A; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Gupta AK; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Bajpai L; Department of Analytical Research & Development, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India., Bagadi M; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India. Electronic address: muralidhararao.b@syngeneintl.com., Mathur A; Small Molecule Drug Discovery, Bristol Myers Squibb Research and Development, P.O. Box 5400, Princeton, NJ 08543-4000, USA. |
| Source: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2022 Apr 01; Vol. 212, pp. 114675. Date of Electronic Publication: 2022 Feb 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 35192992 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chauthe+SK%22">Chauthe SK</searchLink>; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Sidduri+P%22">Sidduri P</searchLink>; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Reddy+M%22">Reddy M</searchLink>; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Sistla+R%22">Sistla R</searchLink>; Department of Medicinal Chemistry, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Byri+V%22">Byri V</searchLink>; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Uttaravalli+MD%22">Uttaravalli MD</searchLink>; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Botlagunta+M%22">Botlagunta M</searchLink>; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Kumar+H%22">Kumar H</searchLink>; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Gupta+A%22">Gupta A</searchLink>; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Gupta+AK%22">Gupta AK</searchLink>; Department of Discovery Synthesis, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Bajpai+L%22">Bajpai L</searchLink>; Department of Analytical Research & Development, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Bagadi+M%22">Bagadi M</searchLink>; Discovery Analytical Sciences, Biocon Bristol Myers Squibb Research & Development Center (BBRC), Bangalore, India. Electronic address: muralidhararao.b@syngeneintl.com.<br /><searchLink fieldCode="AU" term="%22Mathur+A%22">Mathur A</searchLink>; Small Molecule Drug Discovery, Bristol Myers Squibb Research and Development, P.O. Box 5400, Princeton, NJ 08543-4000, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228309336%22">Journal of pharmaceutical and biomedical analysis</searchLink> [J Pharm Biomed Anal] 2022 Apr 01; Vol. 212, pp. 114675. <i>Date of Electronic Publication: </i>2022 Feb 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8309336 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-264X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207317085%22">07317085 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Biomed Anal <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35192992 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jpba.2022.114675 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 114675 Titles: – TitleFull: RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chauthe SK – PersonEntity: Name: NameFull: Sidduri P – PersonEntity: Name: NameFull: Reddy M – PersonEntity: Name: NameFull: Sistla R – PersonEntity: Name: NameFull: Byri V – PersonEntity: Name: NameFull: Uttaravalli MD – PersonEntity: Name: NameFull: Botlagunta M – PersonEntity: Name: NameFull: Kumar H – PersonEntity: Name: NameFull: Gupta A – PersonEntity: Name: NameFull: Gupta AK – PersonEntity: Name: NameFull: Bajpai L – PersonEntity: Name: NameFull: Bagadi M – PersonEntity: Name: NameFull: Mathur A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2022 Apr 01 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1873-264X Numbering: – Type: volume Value: 212 Titles: – TitleFull: Journal of pharmaceutical and biomedical analysis Type: main |
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