Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.

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Title: Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.
Authors: Lee MX; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Wong ALA; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ow S; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Sundar R; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Tan DSP; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Soo RA; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Chee CE; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lim JSJ; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Yong WP; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lim SE; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Goh BC; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Wang L; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee SC; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore. csilsc@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. csilsc@nus.edu.sg.
Source: Targeted oncology [Target Oncol] 2022 Mar; Vol. 17 (2), pp. 141-151. Date of Electronic Publication: 2022 Feb 23.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1776-260X
DOI:10.1007/s11523-022-00867-0