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Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.

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Title: Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.
Authors: Lee MX; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Wong ALA; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ow S; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Sundar R; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Tan DSP; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Soo RA; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Chee CE; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lim JSJ; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Yong WP; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lim SE; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore., Goh BC; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Wang L; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee SC; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore. csilsc@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. csilsc@nus.edu.sg.
Source: Targeted oncology [Target Oncol] 2022 Mar; Vol. 17 (2), pp. 141-151. Date of Electronic Publication: 2022 Feb 23.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.
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  Data: <searchLink fieldCode="AU" term="%22Lee+MX%22">Lee MX</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+ALA%22">Wong ALA</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ow+S%22">Ow S</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Sundar+R%22">Sundar R</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+DSP%22">Tan DSP</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Soo+RA%22">Soo RA</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chee+CE%22">Chee CE</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+JSJ%22">Lim JSJ</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yong+WP%22">Yong WP</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+SE%22">Lim SE</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+BC%22">Goh BC</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+SC%22">Lee SC</searchLink>; Department of Haematology-Oncology, National University Cancer Institute, Level 7, NUHS Tower Block, 1E Kent Ridge Road, Singapore, 119228, Singapore. csilsc@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. csilsc@nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101270595%22">Targeted oncology</searchLink> [Target Oncol] 2022 Mar; Vol. 17 (2), pp. 141-151. <i>Date of Electronic Publication: </i>2022 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+France%22">Springer-Verlag France </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>101270595 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1776-260X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217762596%22">17762596 </searchLink><i>NLM ISO Abbreviation: </i>Target Oncol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s11523-022-00867-0
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      – Code: eng
        Text: English
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        StartPage: 141
    Titles:
      – TitleFull: Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.
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            – D: 01
              M: 03
              Text: 2022 Mar
              Type: published
              Y: 2022
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