Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.

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Title: Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.
Authors: Park VS; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Sun MJS; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Frey WD; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Williams LG; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Hodel KP; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Strauss JD; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Wellens SJ; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Jackson JG; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA., Pursell ZF; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.
Source: NAR cancer [NAR Cancer] 2022 Mar 03; Vol. 4 (1), pp. zcac004. Date of Electronic Publication: 2022 Mar 03 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: PubMed not MEDLINE
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  Data: Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.
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  Data: <searchLink fieldCode="AU" term="%22Park+VS%22">Park VS</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Sun+MJS%22">Sun MJS</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Frey+WD%22">Frey WD</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+LG%22">Williams LG</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Hodel+KP%22">Hodel KP</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Strauss+JD%22">Strauss JD</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Wellens+SJ%22">Wellens SJ</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Jackson+JG%22">Jackson JG</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.<br /><searchLink fieldCode="AU" term="%22Pursell+ZF%22">Pursell ZF</searchLink>; Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101769553%22">NAR cancer</searchLink> [NAR Cancer] 2022 Mar 03; Vol. 4 (1), pp. zcac004. <i>Date of Electronic Publication: </i>2022 Mar 03 (<i>Print Publication: </i>2022).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101769553 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-8674 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226328674%22">26328674 </searchLink><i>NLM ISO Abbreviation: </i>NAR Cancer <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1093/narcan/zcac004
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      – TitleFull: Mouse model and human patient data reveal critical roles for Pten and p53 in suppressing POLE mutant tumor development.
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              Text: 2022 Mar 03
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