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Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.

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Title: Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.
Authors: Struve N; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hoffer K; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weik AS; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Riepen B; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Krug L; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Cetin MH; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Burmester J; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ott L; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Liebing J; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Gatzemeier F; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Müller-Goebel J; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Gerbach M; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bußmann L; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Otolaryngology and Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Laboratory of Radiobiology & Experimental Radiation, Germany., Parplys AC; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Radiotherapy and Radiooncology, Philipps University, Marburg, Germany., Unger K; Research Unit Radiation Cytogenetics, Helmholtz Zentrum München, Oberschleibheim, Germany., Mansour WY; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schüller U; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center Hamburg, Hamburg, Germany., Rieckmann T; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Otolaryngology and Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Laboratory of Radiobiology & Experimental Radiation, Germany., Petersen C; Department of Radiotherapy and Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Rothkamm K; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Short SC; Leeds Institute of Cancer and Pathology, St James's University Hospital, UK., Kriegs M; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Source: Neuro-oncology advances [Neurooncol Adv] 2021 Dec 04; Vol. 4 (1), pp. vdab180. Date of Electronic Publication: 2021 Dec 04 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755003 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-2498 (Electronic) Linking ISSN: 26322498 NLM ISO Abbreviation: Neurooncol Adv Subsets: PubMed not MEDLINE
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  Data: Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.
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  Data: <searchLink fieldCode="AU" term="%22Struve+N%22">Struve N</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffer+K%22">Hoffer K</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weik+AS%22">Weik AS</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Riepen+B%22">Riepen B</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Krug+L%22">Krug L</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cetin+MH%22">Cetin MH</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Burmester+J%22">Burmester J</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ott+L%22">Ott L</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Liebing+J%22">Liebing J</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gatzemeier+F%22">Gatzemeier F</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Goebel+J%22">Müller-Goebel J</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gerbach+M%22">Gerbach M</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bußmann+L%22">Bußmann L</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Otolaryngology and Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Laboratory of Radiobiology & Experimental Radiation, Germany.<br /><searchLink fieldCode="AU" term="%22Parplys+AC%22">Parplys AC</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Radiotherapy and Radiooncology, Philipps University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Unger+K%22">Unger K</searchLink>; Research Unit Radiation Cytogenetics, Helmholtz Zentrum München, Oberschleibheim, Germany.<br /><searchLink fieldCode="AU" term="%22Mansour+WY%22">Mansour WY</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Mildred-Scheel Cancer Career Center HATRICs4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schüller+U%22">Schüller U</searchLink>; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center Hamburg, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rieckmann+T%22">Rieckmann T</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Otolaryngology and Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Laboratory of Radiobiology & Experimental Radiation, Germany.<br /><searchLink fieldCode="AU" term="%22Petersen+C%22">Petersen C</searchLink>; Department of Radiotherapy and Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rothkamm+K%22">Rothkamm K</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Short+SC%22">Short SC</searchLink>; Leeds Institute of Cancer and Pathology, St James's University Hospital, UK.<br /><searchLink fieldCode="AU" term="%22Kriegs+M%22">Kriegs M</searchLink>; Department of Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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