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Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy.

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Title: Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy.
Authors: Vyas A; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232., Gomez-Casal R; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213., Cruz-Rangel S; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232., Villanueva H; Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030., Sikora AG; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Rajagopalan P; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA 19104., Basu D; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA 19104., Pacheco J; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15260., Hammond GRV; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15260., Kiselyov K; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Duvvuri U; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232.; Section of Otolaryngology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 22; Vol. 119 (12), pp. e2100670119. Date of Electronic Publication: 2022 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Vyas+A%22">Vyas A</searchLink>; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232.<br /><searchLink fieldCode="AU" term="%22Gomez-Casal+R%22">Gomez-Casal R</searchLink>; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.<br /><searchLink fieldCode="AU" term="%22Cruz-Rangel+S%22">Cruz-Rangel S</searchLink>; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232.<br /><searchLink fieldCode="AU" term="%22Villanueva+H%22">Villanueva H</searchLink>; Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030.<br /><searchLink fieldCode="AU" term="%22Sikora+AG%22">Sikora AG</searchLink>; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030.<br /><searchLink fieldCode="AU" term="%22Rajagopalan+P%22">Rajagopalan P</searchLink>; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Basu+D%22">Basu D</searchLink>; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Pacheco+J%22">Pacheco J</searchLink>; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15260.<br /><searchLink fieldCode="AU" term="%22Hammond+GRV%22">Hammond GRV</searchLink>; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15260.<br /><searchLink fieldCode="AU" term="%22Kiselyov+K%22">Kiselyov K</searchLink>; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260.<br /><searchLink fieldCode="AU" term="%22Duvvuri+U%22">Duvvuri U</searchLink>; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.; UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232.; Section of Otolaryngology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2022 Mar 22; Vol. 119 (12), pp. e2100670119. <i>Date of Electronic Publication: </i>2022 Mar 14.
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