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Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions.

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Title: Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions.
Authors: Mochizuki T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Zamek-Gliszczynski MJ; Drug Metabolism and Disposition, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Yoshida K; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA., Mao J; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA., Taskar K; Drug Metabolism and Disposition, GlaxoSmithKline, Stevenage, UK., Hirabayashi H; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Chu X; Merck & Co., Inc., Rahway, New Jersey, USA., Lai Y; Drug Metabolism Department, Gilead Sciences Inc., Foster City, California, USA., Takashima T; Laboratory for Safety Assessment & ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Shizuoka, Japan., Rockich K; Drug Metabolism, Pharmacokinetics and Clinical Pharmacology, Incyte Research Institute, Wilmington, Delaware, USA., Yamaura Y; Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd, Osaka, Japan., Fujiwara K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Mizuno T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Maeda K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Furihata K; P-One Clinic, Keikokai Medical Corp., Tokyo, Japan., Sugiyama Y; Sugiyama Laboratory, RIKEN Baton Zone Program, RIKEN Cluster for Science, Technology and Innovation Hub, RIKEN, Yokohama, Kanagawa, Japan., Kusuhara H; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Jun; Vol. 111 (6), pp. 1315-1323. Date of Electronic Publication: 2022 Apr 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions.
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  Data: <searchLink fieldCode="AU" term="%22Mochizuki+T%22">Mochizuki T</searchLink>; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Zamek-Gliszczynski+MJ%22">Zamek-Gliszczynski MJ</searchLink>; Drug Metabolism and Disposition, GlaxoSmithKline, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Yoshida+K%22">Yoshida K</searchLink>; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Mao+J%22">Mao J</searchLink>; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Taskar+K%22">Taskar K</searchLink>; Drug Metabolism and Disposition, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Hirabayashi+H%22">Hirabayashi H</searchLink>; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Chu+X%22">Chu X</searchLink>; Merck & Co., Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Lai+Y%22">Lai Y</searchLink>; Drug Metabolism Department, Gilead Sciences Inc., Foster City, California, USA.<br /><searchLink fieldCode="AU" term="%22Takashima+T%22">Takashima T</searchLink>; Laboratory for Safety Assessment & ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Rockich+K%22">Rockich K</searchLink>; Drug Metabolism, Pharmacokinetics and Clinical Pharmacology, Incyte Research Institute, Wilmington, Delaware, USA.<br /><searchLink fieldCode="AU" term="%22Yamaura+Y%22">Yamaura Y</searchLink>; Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fujiwara+K%22">Fujiwara K</searchLink>; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mizuno+T%22">Mizuno T</searchLink>; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Maeda+K%22">Maeda K</searchLink>; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Furihata+K%22">Furihata K</searchLink>; P-One Clinic, Keikokai Medical Corp., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sugiyama+Y%22">Sugiyama Y</searchLink>; Sugiyama Laboratory, RIKEN Baton Zone Program, RIKEN Cluster for Science, Technology and Innovation Hub, RIKEN, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kusuhara+H%22">Kusuhara H</searchLink>; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
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