In vivo prime editing of a metabolic liver disease in mice.
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| Title: | In vivo prime editing of a metabolic liver disease in mice. |
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| Authors: | Böck D; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland., Rothgangl T; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland., Villiger L; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland., Schmidheini L; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland.; Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland., Matsushita M; Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland., Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland., Ioannidi E; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland., Rimann N; Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, 8032 Zürich, Switzerland., Grisch-Chan HM; Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, 8032 Zürich, Switzerland., Kreutzer S; Genome Engineering and Measurement Laboratory (GEML), ETH Zürich, 8093 Zürich, Switzerland.; Functional Genomics Center Zurich, ETH Zürich/University of Zurich, 8057 Zürich, Switzerland., Kontarakis Z; Genome Engineering and Measurement Laboratory (GEML), ETH Zürich, 8093 Zürich, Switzerland.; Functional Genomics Center Zurich, ETH Zürich/University of Zurich, 8057 Zürich, Switzerland., Kopf M; Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland., Thöny B; Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, 8032 Zürich, Switzerland.; Zurich Center for Integrative Human Physiology, 8006 Zürich, Switzerland.; Neuroscience Center Zurich, 8057 Zürich, Switzerland., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, 8057 Zürich, Switzerland. |
| Source: | Science translational medicine [Sci Transl Med] 2022 Mar 16; Vol. 14 (636), pp. eabl9238. Date of Electronic Publication: 2022 Mar 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.abl9238 |
