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Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.

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Title: Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.
Authors: Puskarich MA; Department of Emergency Medicine, University of Minnesota, Minneapolis.; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota., Ingraham NE; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis., Merck LH; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville., Driver BE; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota., Wacker DA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis., Black LP; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville., Jones AE; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson., Fletcher CV; Center for Drug Discovery, University of Nebraska Medical Center, Omaha., South AM; Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, Winston Salem, North Carolina.; Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina.; Department of Surgery-Hypertension and Vascular Research, Wake Forest School of Medicine, Winston Salem, North Carolina., Murray TA; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Lewandowski C; Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan., Farhat J; Department of Surgery, North Memorial Medical Center, Minneapolis, Minnesota., Benoit JL; Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio., Biros MH; Department of Emergency Medicine, University of Minnesota, Minneapolis., Cherabuddi K; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville., Chipman JG; Department of Surgery, University of Minnesota, Minneapolis., Schacker TW; Division of Infectious Disease, Department of Medicine, University of Minnesota, Minneapolis., Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville., Voelker HT; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Koopmeiners JS; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Tignanelli CJ; Department of Surgery, University of Minnesota, Minneapolis.
Corporate Authors: Angiotensin Receptor Blocker Based Lung Protective Strategies for Inpatients With COVID-19 (ALPS-IP) Investigators
Source: JAMA network open [JAMA Netw Open] 2022 Mar 01; Vol. 5 (3), pp. e222735. Date of Electronic Publication: 2022 Mar 01.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Puskarich+MA%22">Puskarich MA</searchLink>; Department of Emergency Medicine, University of Minnesota, Minneapolis.; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Ingraham+NE%22">Ingraham NE</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Merck+LH%22">Merck LH</searchLink>; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville.<br /><searchLink fieldCode="AU" term="%22Driver+BE%22">Driver BE</searchLink>; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Wacker+DA%22">Wacker DA</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Black+LP%22">Black LP</searchLink>; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville.<br /><searchLink fieldCode="AU" term="%22Jones+AE%22">Jones AE</searchLink>; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson.<br /><searchLink fieldCode="AU" term="%22Fletcher+CV%22">Fletcher CV</searchLink>; Center for Drug Discovery, University of Nebraska Medical Center, Omaha.<br /><searchLink fieldCode="AU" term="%22South+AM%22">South AM</searchLink>; Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, Winston Salem, North Carolina.; Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina.; Department of Surgery-Hypertension and Vascular Research, Wake Forest School of Medicine, Winston Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Murray+TA%22">Murray TA</searchLink>; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Lewandowski+C%22">Lewandowski C</searchLink>; Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Farhat+J%22">Farhat J</searchLink>; Department of Surgery, North Memorial Medical Center, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Benoit+JL%22">Benoit JL</searchLink>; Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Biros+MH%22">Biros MH</searchLink>; Department of Emergency Medicine, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Cherabuddi+K%22">Cherabuddi K</searchLink>; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville.<br /><searchLink fieldCode="AU" term="%22Chipman+JG%22">Chipman JG</searchLink>; Department of Surgery, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Schacker+TW%22">Schacker TW</searchLink>; Division of Infectious Disease, Department of Medicine, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Guirgis+FW%22">Guirgis FW</searchLink>; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville.<br /><searchLink fieldCode="AU" term="%22Voelker+HT%22">Voelker HT</searchLink>; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Koopmeiners+JS%22">Koopmeiners JS</searchLink>; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Tignanelli+CJ%22">Tignanelli CJ</searchLink>; Department of Surgery, University of Minnesota, Minneapolis.
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  Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2022 Mar 01; Vol. 5 (3), pp. e222735. <i>Date of Electronic Publication: </i>2022 Mar 01.
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