CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.
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| Title: | CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element. |
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| Authors: | Teghanemt A; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA., Pulipati P; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA., Misel-Wuchter K; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Molecular Medicine Graduate Program, Iowa City, IA, 52242, USA., Day K; Zymo Research Corporation, Irvine, CA, USA., Yorek MS; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA., Yi R; Department of Computer Science, New York University, New York, NY, 10011, USA., Keen HL; Bioinformatics Division of the Iowa Institute of Human Genetics, University of Iowa, Iowa City, IA, 52242, USA., Au C; The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, 10016, USA., Maretzky T; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA., Gurung P; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA., Littman DR; The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, 10016, USA.; Howard Hughes Medical Institute, New York, NY, 10016, USA., Issuree PD; Inflammation Program, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA. Priya-issuree@uiowa.edu.; Department of Internal Medicine, Roy J. and Lucille A, Carver College of Medicine University of Iowa, Iowa City, IA, 52242, USA. Priya-issuree@uiowa.edu.; Molecular Medicine Graduate Program, Iowa City, IA, 52242, USA. Priya-issuree@uiowa.edu.; Immunology Graduate Program, Iowa City, IA, 52242, USA. Priya-issuree@uiowa.edu. |
| Source: | Nature communications [Nat Commun] 2022 Mar 18; Vol. 13 (1), pp. 1477. Date of Electronic Publication: 2022 Mar 18. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-28914-4 |