Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19.
Saved in:
| Title: | Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19. |
|---|---|
| Authors: | Apostolidis SA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Sarkar A; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States., Giannini HM; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Goel RR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Mathew D; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Suzuki A; Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, United States., Baxter AE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Greenplate AR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Immune Health™, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Alanio C; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Abdel-Hakeem M; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Oldridge DA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Giles JR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Wu JE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Chen Z; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Huang YJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Belman J; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Pattekar A; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Immune Health™, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Manne S; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Kuthuru O; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Dougherty J; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Weiderhold B; Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, United States., Weisman AR; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Ittner CAG; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Gouma S; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Dunbar D; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Frank I; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Huang AC; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Vella LA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Reilly JP; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Hensley SE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Rauova L; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Zhao L; Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, United States., Meyer NJ; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Poncz M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Abrams CS; Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, United States., Wherry EJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Immune Health™, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States. |
| Corporate Authors: | UPenn COVID Processing Unit |
| Source: | Frontiers in immunology [Front Immunol] 2022 Mar 03; Vol. 13, pp. 834988. Date of Electronic Publication: 2022 Mar 03 (Print Publication: 2022). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1664-3224 |
|---|---|
| DOI: | 10.3389/fimmu.2022.834988 |
