View in EDS

NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24.

Saved in:
Bibliographic Details
Title: NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24.
Authors: Torres F; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Walser R; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Kaderli J; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Rossi E; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Bobby R; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Packer MJ; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Sarda S; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Walker G; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom., Hitchin JR; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom., Milbradt AG; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Orts J; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.; Department of Pharmaceutical Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
Source: Journal of medicinal chemistry [J Med Chem] 2022 Apr 14; Vol. 65 (7), pp. 5565-5574. Date of Electronic Publication: 2022 Mar 31.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 35357834
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Torres+F%22">Torres F</searchLink>; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Walser+R%22">Walser R</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaderli+J%22">Kaderli J</searchLink>; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rossi+E%22">Rossi E</searchLink>; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bobby+R%22">Bobby R</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Packer+MJ%22">Packer MJ</searchLink>; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sarda+S%22">Sarda S</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Walker+G%22">Walker G</searchLink>; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hitchin+JR%22">Hitchin JR</searchLink>; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Milbradt+AG%22">Milbradt AG</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Orts+J%22">Orts J</searchLink>; Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, HCI F217, Eidgenossische Technische Hochschule Zurich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.; Department of Pharmaceutical Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2022 Apr 14; Vol. 65 (7), pp. 5565-5574. <i>Date of Electronic Publication: </i>2022 Mar 31.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35357834
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acs.jmedchem.1c01703
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 5565
    Titles:
      – TitleFull: NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Torres F
      – PersonEntity:
          Name:
            NameFull: Walser R
      – PersonEntity:
          Name:
            NameFull: Kaderli J
      – PersonEntity:
          Name:
            NameFull: Rossi E
      – PersonEntity:
          Name:
            NameFull: Bobby R
      – PersonEntity:
          Name:
            NameFull: Packer MJ
      – PersonEntity:
          Name:
            NameFull: Sarda S
      – PersonEntity:
          Name:
            NameFull: Walker G
      – PersonEntity:
          Name:
            NameFull: Hitchin JR
      – PersonEntity:
          Name:
            NameFull: Milbradt AG
      – PersonEntity:
          Name:
            NameFull: Orts J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 14
              M: 04
              Text: 2022 Apr 14
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1520-4804
          Numbering:
            – Type: volume
              Value: 65
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Journal of medicinal chemistry
              Type: main
ResultId 1