Phase 1 Clinical Trial Evaluating the Safety and Anti-Tumor Activity of ADP-A2M10 SPEAR T-Cells in Patients With MAGE-A10+ Head and Neck, Melanoma, or Urothelial Tumors.

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Title: Phase 1 Clinical Trial Evaluating the Safety and Anti-Tumor Activity of ADP-A2M10 SPEAR T-Cells in Patients With MAGE-A10+ Head and Neck, Melanoma, or Urothelial Tumors.
Authors: Hong DS; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Butler MO; Princess Margaret Hospital Cancer Centre, University of Toronto, Toronto, ON, Canada., Pachynski RK; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States., Sullivan R; Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Kebriaei P; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Boross-Harmer S; Princess Margaret Hospital Cancer Centre, University of Toronto, Toronto, ON, Canada., Ghobadi A; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States., Frigault MJ; Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Dumbrava EE; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Sauer A; Adaptimmune LLC, Philadelphia, PA, United States., Brophy F; Adaptimmune LLC, Philadelphia, PA, United States., Navenot JM; Adaptimmune LLC, Philadelphia, PA, United States., Fayngerts S; Adaptimmune LLC, Philadelphia, PA, United States., Wolchinsky Z; Adaptimmune Limited, Abingdon, United Kingdom., Broad R; Adaptimmune Limited, Abingdon, United Kingdom., Batrakou DG; Adaptimmune LLC, Philadelphia, PA, United States., Wang R; Adaptimmune Limited, Abingdon, United Kingdom., Solis LM; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Duose DY; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Sanderson JP; Adaptimmune Limited, Abingdon, United Kingdom., Gerry AB; Adaptimmune Limited, Abingdon, United Kingdom., Marks D; Adaptimmune LLC, Philadelphia, PA, United States., Bai J; Adaptimmune LLC, Philadelphia, PA, United States., Norry E; Adaptimmune LLC, Philadelphia, PA, United States., Fracasso PM; Adaptimmune LLC, Philadelphia, PA, United States.
Source: Frontiers in oncology [Front Oncol] 2022 Mar 18; Vol. 12, pp. 818679. Date of Electronic Publication: 2022 Mar 18 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2234-943X
DOI:10.3389/fonc.2022.818679