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FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.

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Title: FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Authors: Junqueira C; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. caroline.junqueira@childrens.harvard.edu.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. caroline.junqueira@childrens.harvard.edu.; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil. caroline.junqueira@childrens.harvard.edu., Crespo Â; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Ranjbar S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., de Lacerda LB; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil., Lewandrowski M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Ingber J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Parry B; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA., Ravid S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Clark S; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Schrimpf MR; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Ho F; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Beakes C; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA., Margolin J; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA., Russell N; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA., Kays K; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA., Boucau J; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Cambridge, MA, USA., Das Adhikari U; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Cambridge, MA, USA., Vora SM; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Leger V; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Gehrke L; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Henderson LA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Immunology, Boston Children's Hospital, Boston, MA, USA., Janssen E; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Immunology, Boston Children's Hospital, Boston, MA, USA., Kwon D; Ragon Institute, Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Cambridge, MA, USA., Sander C; cBio Center, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Abraham J; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Goldberg MB; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Center for Bacterial Pathogenesis, Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA., Wu H; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Mehta G; Institute for Liver and Digestive Health, University College London, London, UK.; Institute of Hepatology, Foundation for Liver Research, London, UK., Bell S; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Goldfeld AE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Filbin MR; Emergency Medicine, Institute for Patient Care, Massachusetts General Hospital, Boston, MA, USA. mfilbin@mgh.harvard.edu., Lieberman J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. judy.lieberman@childrens.harvard.edu.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. judy.lieberman@childrens.harvard.edu.
Source: Nature [Nature] 2022 Jun; Vol. 606 (7914), pp. 576-584. Date of Electronic Publication: 2022 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Goldberg+MB%22">Goldberg MB</searchLink>; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Center for Bacterial Pathogenesis, Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mehta+G%22">Mehta G</searchLink>; Institute for Liver and Digestive Health, University College London, London, UK.; Institute of Hepatology, Foundation for Liver Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Bell+S%22">Bell S</searchLink>; 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