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Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia.

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Title: Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia.
Authors: Palmer DS; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. duncan.stuart.palmer@gmail.com.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. duncan.stuart.palmer@gmail.com., Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chapman SB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adolfsson R; Department of Clinical Sciences, Psychiatry, Umea University, Umea, Sweden., Bass N; Division of Psychiatry, University College London, London, UK., Blackwood D; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Boks MPM; Department of Psychiatry, Brain Center UMC Utrecht, Utrecht, the Netherlands., Chen CY; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Biogen, Cambridge, MA, USA., Churchhouse C; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Corvin AP; Trinity College Dublin, Dublin, Ireland., Craddock N; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Curtis D; UCL Genetics Institute, University College London, London, UK.; Centre for Psychiatry, Queen Mary University of London, London, UK., Di Florio A; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Dickerson F; Sheppard Pratt, Baltimore, MD, USA., Freimer NB; Department of Psychiatry and Biobehavioral Science, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Goes FS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Jia X; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Jones I; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Division of Psychiatry and Clinical Neurosciences, Cardiff University, Cardiff, UK., Jones L; Department of Psychological Medicine, University of Worcester, Worcester, UK., Jonsson L; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Kahn RS; Division of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Landén M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Locke AE; Division of Genomics & Bioinformatics and McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., McQuillin A; Division of Psychiatry, University College London, London, UK., Morris DW; Centre for Neuroimaging, Cognition and Genomics, Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland., O'Donovan MC; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Ophoff RA; Department of Psychiatry and Biobehavioral Science, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, Erasmus Medical Center, Erasmus University, Rotterdam, the Netherlands., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychiatry, University Hospital Frankfurt - Goethe University, Frankfurt, Germany., Risch N; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Schaefer C; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Scott L; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Singh T; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Solomonson M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Clair DS; Institute for Medical Sciences, University of Aberdeen, Aberdeen, UK., Stahl EA; Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Vreeker A; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Sophia Children Hospital, Erasmus University, Rotterdam, the Netherlands., Walters JTR; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Wang W; Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Watts NA; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yolken R; Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, MD, USA., Zandi PP; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. bneale@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. bneale@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. bneale@broadinstitute.org.
Source: Nature genetics [Nat Genet] 2022 May; Vol. 54 (5), pp. 541-547. Date of Electronic Publication: 2022 Apr 11.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia.
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              Value: 5
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1