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A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis.

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Title: A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis.
Authors: Khalid U; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany., Simovic M; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany., Hammann LA; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany., Iskar M; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Wong JKL; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Kumar R; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jugold M; Core Facility, Small Animal Imaging Center, DKFZ, Heidelberg, Germany., Sill M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Bolkestein M; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kolb T; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hergt M; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Devens F; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ecker J; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Kool M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Milde T; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center and German Consortium for Translational Cancer Research, Heidelberg, Germany.; KiTZ Clinical Trial Unit, Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Westermann F; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Benner A; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Lewis J; European Molecular Biology Laboratory, Heidelberg, Germany., Dietrich S; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Pfister SM; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; KiTZ Clinical Trial Unit, Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Lichter P; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Zapatka M; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Ernst A; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Source: International journal of cancer [Int J Cancer] 2022 Aug 15; Vol. 151 (4), pp. 590-606. Date of Electronic Publication: 2022 Apr 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis.
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  Data: <searchLink fieldCode="AU" term="%22Khalid+U%22">Khalid U</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Simovic+M%22">Simovic M</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hammann+LA%22">Hammann LA</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Iskar+M%22">Iskar M</searchLink>; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wong+JKL%22">Wong JKL</searchLink>; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kumar+R%22">Kumar R</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jugold+M%22">Jugold M</searchLink>; Core Facility, Small Animal Imaging Center, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sill+M%22">Sill M</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Bolkestein+M%22">Bolkestein M</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kolb+T%22">Kolb T</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hergt+M%22">Hergt M</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Devens+F%22">Devens F</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ecker+J%22">Ecker J</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kool+M%22">Kool M</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Milde+T%22">Milde T</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center and German Consortium for Translational Cancer Research, Heidelberg, Germany.; KiTZ Clinical Trial Unit, Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Westermann+F%22">Westermann F</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Benner+A%22">Benner A</searchLink>; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lewis+J%22">Lewis J</searchLink>; European Molecular Biology Laboratory, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dietrich+S%22">Dietrich S</searchLink>; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pfister+SM%22">Pfister SM</searchLink>; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; KiTZ Clinical Trial Unit, Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lichter+P%22">Lichter P</searchLink>; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Zapatka+M%22">Zapatka M</searchLink>; Division of Molecular Genetics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ernst+A%22">Ernst A</searchLink>; Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2022 Aug 15; Vol. 151 (4), pp. 590-606. <i>Date of Electronic Publication: </i>2022 Apr 28.
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