Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection.

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Title: Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection.
Authors: Ko ER; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Hospital Medicine, Division of General Internal Medicine, Duke University School of Medicine, Durham, North Carolina., Henao R; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Department of Biostatistics and Informatics, Duke University, Durham, North Carolina.; Duke Clinical Research Institute, Durham, North Carolina., Frankey K; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina., Petzold EA; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina., Isner PD; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina., Jaehne AK; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan., Allen N; Department of Pediatrics, Henry Ford Hospital System, Detroit, Michigan., Gardner-Gray J; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan.; Department of Medicine, Henry Ford Hospital System, Detroit, Michigan.; Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital System, Detroit, Michigan., Hurst G; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan.; Department of Medicine, Henry Ford Hospital System, Detroit, Michigan.; Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital System, Detroit, Michigan., Pflaum-Carlson J; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan.; Department of Medicine, Henry Ford Hospital System, Detroit, Michigan.; Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital System, Detroit, Michigan., Jayaprakash N; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan.; Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital System, Detroit, Michigan., Rivers EP; Department of Emergency Medicine, Henry Ford Hospital System, Detroit, Michigan.; Department of Surgery, Henry Ford Hospital System, Detroit, Michigan., Wang H; McGovern Medical University of Texas Health, Houston.; Department of Emergency Medicine, The Ohio State University, Columbus., Ugalde I; McGovern Medical University of Texas Health, Houston., Amanullah S; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island., Mercurio L; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island., Chun TH; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island., May L; Department of Emergency Medicine, University of California, Davis., Hickey RW; Division of Pediatric Emergency Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania., Lazarus JE; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Gunaratne SH; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York., Pallin DJ; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Jambaulikar G; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Huckins DS; Department of Emergency Medicine, Newton-Wellesley Hospital, Boston, Massachusetts., Ampofo K; Department of Pediatrics, University of Utah, Salt Lake City., Jhaveri R; Department of Pediatrics, University of North Carolina at Chapel Hill.; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Jiang Y; The Biostatistics Center, George Washington University, Rockville, Maryland., Komarow L; The Biostatistics Center, George Washington University, Rockville, Maryland., Evans SR; The Biostatistics Center, George Washington University, Rockville, Maryland., Ginsburg GS; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina., Tillekeratne LG; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.; Medical Service, Durham Veterans Affairs Health Care System, Durham, North Carolina., McClain MT; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.; Medical Service, Durham Veterans Affairs Health Care System, Durham, North Carolina., Burke TW; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina., Woods CW; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.; Medical Service, Durham Veterans Affairs Health Care System, Durham, North Carolina., Tsalik EL; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.; Emergency Medicine Service, Durham Veterans Affairs Health Care System, Durham, North Carolina.
Corporate Authors: Antibacterial Resistance Leadership Group
Source: JAMA network open [JAMA Netw Open] 2022 Apr 01; Vol. 5 (4), pp. e227299. Date of Electronic Publication: 2022 Apr 01.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection.
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McGovern Medical University of Texas Health, Houston.<br /><searchLink fieldCode="AU" term="%22Amanullah+S%22">Amanullah S</searchLink>; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22Mercurio+L%22">Mercurio L</searchLink>; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22Chun+TH%22">Chun TH</searchLink>; Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22May+L%22">May L</searchLink>; 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