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Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.

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Title: Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.
Authors: Zhang R; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Chen D; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA., Fan H; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Wu R; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Tu J; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Zhang FQ; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Wang M; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA., Zheng H; Department of Pediatrics and Aflac Cancer and Blood Disorder Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA., Qu CK; Department of Pediatrics and Aflac Cancer and Blood Disorder Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA., Elf SE; The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA., Faubert B; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., He YY; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Bissonnette MB; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Gao X; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address: xgao30@uchicago.edu., DeBerardinis RJ; UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ralph.deberardinis@utsouthwestern.edu., Chen J; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address: jingchen@medicine.bsd.uchicago.edu.
Source: Cell chemical biology [Cell Chem Biol] 2022 Jul 21; Vol. 29 (7), pp. 1200-1208.e6. Date of Electronic Publication: 2022 Apr 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+R%22">Zhang R</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Fan+H%22">Fan H</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Wu+R%22">Wu R</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Tu+J%22">Tu J</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+FQ%22">Zhang FQ</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Department of Pediatrics and Aflac Cancer and Blood Disorder Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Qu+CK%22">Qu CK</searchLink>; Department of Pediatrics and Aflac Cancer and Blood Disorder Center, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Elf+SE%22">Elf SE</searchLink>; The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Faubert+B%22">Faubert B</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22He+YY%22">He YY</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Bissonnette+MB%22">Bissonnette MB</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address: xgao30@uchicago.edu.<br /><searchLink fieldCode="AU" term="%22DeBerardinis+RJ%22">DeBerardinis RJ</searchLink>; UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ralph.deberardinis@utsouthwestern.edu.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address: jingchen@medicine.bsd.uchicago.edu.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2022 Jul 21; Vol. 29 (7), pp. 1200-1208.e6. <i>Date of Electronic Publication: </i>2022 Apr 15.
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        Value: 10.1016/j.chembiol.2022.03.010
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        Text: English
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