The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading.
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| Title: | The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading. |
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| Authors: | Schweibenz BD; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.; Graduate Program in Biochemistry, Rutgers University, Piscataway, NJ, USA., Devarkar SC; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.; Graduate Program in Biochemistry, Rutgers University, Piscataway, NJ, USA., Solotchi M; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.; Cell and Development Biology, Rutgers University, Piscataway, NJ, USA., Craig C; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.; Graduate Program in Biochemistry, Rutgers University, Piscataway, NJ, USA., Zheng J; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA., Pascal BD; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA., Gokhale S; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Cellular and Molecular Pharmacology, Rutgers University, Piscataway, NJ, USA., Xie P; Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Griffin PR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.; Department of Integrative Structural and Computational Biology, Jupiter, FL, USA., Patel SS; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA. |
| Source: | The EMBO journal [EMBO J] 2022 May 16; Vol. 41 (10), pp. e109782. Date of Electronic Publication: 2022 Apr 19. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.15252/embj.2021109782 |
